156414-59-4

Basic information

• Product Name: 5-Hexen-2-one, 1-methoxy-1-(phenylsulfonyl)-5-[(trimethylsilyl)methyl]-
• CAS NO: 156414-59-4
• Molecular Formula: C17H26O4SSi
• Molecular Weight: 354.543
• Mol File: 156414-59-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-Hexen-2-one, 1-methoxy-1-(phenylsulfonyl)-5-[(trimethylsilyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hexen-2-one, 1-methoxy-1-(phenylsulfonyl)-5-[(trimethylsilyl)methyl]-(156414-59-4)
• EPA Substance Registry System: 5-Hexen-2-one, 1-methoxy-1-(phenylsulfonyl)-5-[(trimethylsilyl)methyl]-(156414-59-4)

Safety Data

• Hazardous Substances Data: 156414-59-4(Hazardous Substances Data)

Upstream product

• 1156545-87-7 C₁₇H₂₈O₄SSi 
• 13865-50-4 methoxymethyl phenyl sulfide 
• 15251-78-2 phenyl methoxymethyl sulfone 
• 98754-05-3 4-Trimethylsilanylmethyl-pent-4-enoic acid ethyl ester 

Downstream Products

• 1156545-87-7 C₁₇H₂₈O₄SSi 
• 156414-63-0 (1R,2S)-1-[(1R,3R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-methoxy-cyclohexyl]-2-methyl-but-3-en-1-ol 
• 156414-64-1 (1R,2R)-1-[(1R,3R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-methoxy-cyclohexyl]-2-(R)-oxiranyl-propan-1-ol 
• 156414-57-2 tert-Butyl-[(1R,2R,4S)-2-methoxy-4-((R)-(R)-2-oxiranyl-propyl)-cyclohexyloxy]-dimethyl-silane 
• 128209-97-2 (1R,3R,4R)-4-[(tert-butyldimethylsilyl)oxy]-3-methoxycyclohexane-1-carbaldehyde 

Relevant articles and documents

Studies towards the total synthesis of rapamycin: Preparation of the cyclohexyl C33-C42 fragment and further coupling to afford the C22-C42 carbon unit

A short and stereoselective synthesis of the C33-C42 fragment 3 of rapamycin and its coupling with the previously prepared C22-C32 fragment 2 is described. The synthesis of 3 involves the preparation of enantiom

Towards the Synthesis of the C37-C42 Fragment of Rapamycin: Intramolecular Reactions of Allyl Silanes with Oxonium Ions Generated from α-Alkoxy Sulfones.

A new method for the formation of methylene cyclohexane derivatives has been developed, using intramolecular trapping by allyl silanes of oxonium ions generated from α-alkoxysulfones.These acyclic precursors were prepared by quenching the anion of methoxy