156545-07-2 Usage
Description
3,5-DifluoroPhenylboronic acid is an organic compound with the chemical formula C6H4BF2O2H. It is a white to beige-yellowish powder and is commonly used as a reactant in various chemical reactions and synthesis processes. 3,5-DifluoroPhenylboronic acid is known for its versatility and plays a significant role in the production of various pharmaceuticals, organic compounds, and materials.
Uses
1. Used in Pharmaceutical Synthesis:
3,5-DifluoroPhenylboronic acid is used as a reactant for the synthesis of honokiol analogs, which are known as angiogenesis inhibitors. These analogs have potential applications in the treatment of various diseases, including cancer, by inhibiting the formation of new blood vessels that supply tumors with nutrients.
2. Used in Homo-coupling Reactions:
In this application, 3,5-DifluoroPhenylboronic acid serves as a reactant in homo-coupling reactions, which involve the formation of a bond between two identical molecules. This process is essential in the synthesis of various organic compounds and materials.
3. Used in Suzuki-Miyaura Cross-coupling Reactions:
3,5-DifluoroPhenylboronic acid is used as a reactant in Suzuki-Miyaura cross-coupling reactions, a widely used method for the formation of carbon-carbon bonds in organic chemistry. This reaction is crucial in the synthesis of complex organic molecules, including pharmaceuticals and natural products.
4. Used in Enantioselective Borane Reduction:
3,5-DifluoroPhenylboronic acid is used as a reactant in the enantioselective borane reduction of trifluoroacetophenone. This reaction is essential in the synthesis of chiral compounds, which have different spatial arrangements of atoms and are crucial in the development of pharmaceuticals with specific biological activities.
5. Used in the Synthesis of N-thiazol-2-yl-benzamides:
3,5-DifluoroPhenylboronic acid is used as a reactant in the synthesis of N-thiazol-2-yl-benzamides, which are glucokinase (GK) activators. These compounds have potential applications in the treatment of type 2 diabetes mellitus (T2DM) by regulating glucose metabolism and improving insulin sensitivity.
6. Used in the Production of Liquid Crystals:
3,5-DifluoroPhenylboronic acid is used as an intermediate in the production of liquid crystals, which are essential components in the manufacturing of display devices, such as televisions, computer monitors, and smartphones.
Check Digit Verification of cas no
The CAS Registry Mumber 156545-07-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,5,4 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 156545-07:
(8*1)+(7*5)+(6*6)+(5*5)+(4*4)+(3*5)+(2*0)+(1*7)=142
142 % 10 = 2
So 156545-07-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H11BF2O3/c15-12-10(14(17)18)6-7-11(13(12)16)19-8-9-4-2-1-3-5-9/h1-7,17-18H,8H2
156545-07-2Relevant articles and documents
Meso-substituted boron-dipyrromethene compounds: synthesis, tunable solid-state emission, and application in blue-driven LEDs
Liu, Hao,Su, Huan,Chen, Zhiyuan,Zhu, Senqiang,Liu, Rui,Zhu, Hongjun
, p. 1697 - 1705 (2021)
In this work, we depict the synthesis and characterization of a series of meso-substituted boron-dipyrromethene (BODIPY) compounds. Their optical and electrochemical properties were investigated systematically. All these compounds exhibited intense absorption bands in the ultraviolet (UV) and visible regions, which arise from the π–π* transitions based on their BODIPY core segments. By comparing electron-withdrawing substituents and electron-donating substituents, we found that these compounds exhibited some similar photophysical properties but exhibited different fluorescence in the solid state. All compounds were highly emissive in dichloromethane at room temperature (λem = 512–523 nm, ΦPL > 0.9). When these compounds were applied in blue-driven light-emitting diodes (LEDs) as light-emitting materials, the devices showed luminescence efficiency ranging from 1.09 to 34.13 lm/W. Their luminescence and electrochemical properties could be used for understanding the structure–property relationship of BODIPY compounds and developing functional fluorescent materials.
COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE
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Paragraph 0094, (2014/09/30)
The present invention relates to a compound having a 2-fluorophenyloxymethane structure and useful for organic electronic materials and medical and agricultural chemicals, particularly materials for liquid crystal display elements. A problem to be solved
LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT
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Page/Page column 43-44, (2009/12/07)
The invention provides a liquid crystal compound which has stability to heat, light and so forth, shows liquid crystal phases in a wide temperature range, and has a small viscosity, an appropriate optical anisotropy, a large dielectric anisotropy, and an
