1565829-19-7

Basic information

• Product Name: 3-((S)-((2S,4S,8R)-8-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione
• Synonyms: 3-((S)-((2S,4S,8R)-8-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione
• CAS NO: 1565829-19-7
• Molecular Weight: 564.607
• Mol File: 1565829-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-((S)-((2S,4S,8R)-8-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((S)-((2S,4S,8R)-8-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione(1565829-19-7)
• EPA Substance Registry System: 3-((S)-((2S,4S,8R)-8-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione(1565829-19-7)

Safety Data

• Hazardous Substances Data: 1565829-19-7(Hazardous Substances Data)

Upstream product

• 852913-53-2 9-amino-9-deoxy-epihydroquinine 
• 1132827-67-8 3-(methoxy)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione 
• 455-14-1 4-trifluoromethylphenylamine 

Relevant articles and documents

Enantioselective synthesis of enol lactones from tandem Michael addition/lactonization catalyzed by a chiral squaramide catalyst

The enantioselective tandem Michael addition reaction of dimedone and related 1,3-dicarbonyl compounds with α,β-unsaturated N-acylated succinimides catalyzed by a chiral squaramide catalyst has been investigated. This reaction provides a new approach for the synthesis of chiral enol lactones in good yields with moderate to high enantioselectivities (up to 88% ee) through the enantioselective Michael addition followed by lactonization and removal of the succinimide auxiliary.