156624-78-1 Usage
Description
(S)-2H-ISOINDOLE-2-ACETIC ACID, 1,3-DIHYDRO-ALPHA-[(4-METHOXYPHENYL)METHYL]-1,3-DIOXO-, METHYL ESTER is a complex chemical compound with an isoindole-2-acetic acid core, featuring a 1,3-dihydro-alpha-[(4-methoxyphenyl)methyl]-1,3-dioxo side chain and a methyl ester functional group. As a derivative of isoindole-2-acetic acid, a heterocyclic organic compound, this molecule exhibits a unique structure and functional groups that may hold potential pharmacological properties. The presence of the methoxyphenyl group and the methyl ester functionality suggest possible applications in medicinal chemistry and drug development, making it a compound of interest for further investigation in the pharmaceutical and chemical research fields.
Uses
Used in Pharmaceutical Industry:
(S)-2H-ISOINDOLE-2-ACETIC ACID, 1,3-DIHYDRO-ALPHA-[(4-METHOXYPHENYL)METHYL]-1,3-DIOXO-, METHYL ESTER is used as a potential pharmaceutical candidate for the development of new drugs due to its unique structure and functional groups. The methoxyphenyl group and methyl ester functionality may contribute to its interaction with biological targets, potentially leading to the discovery of novel therapeutic agents.
Used in Chemical Research:
In the field of chemical research, (S)-2H-ISOINDOLE-2-ACETIC ACID, 1,3-DIHYDRO-ALPHA-[(4-METHOXYPHENYL)METHYL]-1,3-DIOXO-, METHYL ESTER serves as a subject for studying the synthesis and modification of complex organic molecules. Its unique structure may provide insights into the development of new synthetic pathways and the exploration of novel chemical reactions.
Used in Medicinal Chemistry:
(S)-2H-ISOINDOLE-2-ACETIC ACID, 1,3-DIHYDRO-ALPHA-[(4-METHOXYPHENYL)METHYL]-1,3-DIOXO-, METHYL ESTER is used as a starting material or intermediate in the synthesis of various bioactive compounds. Its structural features may be exploited to design and develop new molecules with potential applications in the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 156624-78-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,6,2 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 156624-78:
(8*1)+(7*5)+(6*6)+(5*6)+(4*2)+(3*4)+(2*7)+(1*8)=151
151 % 10 = 1
So 156624-78-1 is a valid CAS Registry Number.
156624-78-1Relevant articles and documents
Chiral diene-promoted room temperature conjugate arylation: Highly enantioselective synthesis of substituted chiral phenylalanine derivatives and α,α-di(arylmethyl)acetates
Chen, Jian-Ping,Xu, Ming-Hua
supporting information, p. 4569 - 4574 (2020/07/04)
A highly enantiocontrolled room temperature rhodium-catalyzed conjugate arylation process was developed. The reaction proceeds through 1,4-addition of α-substituted acrylates followed by enantioselective protonation using a C1-symmetric chiral bicyclo[2,2,2] diene as the ligand and water as the proton source. This exceptionally simple protocol provides a reliable and practical access to structurally important phenylalanine derivatives and α,α-di(arylmethyl)acetates in high yields (up to 99%) with good to excellent ee values (up to 99%).
Cation Radical Accelerated Nucleophilic Aromatic Substitution via Organic Photoredox Catalysis
Tay, Nicholas E. S.,Nicewicz, David A.
supporting information, p. 16100 - 16104 (2017/11/22)
Nucleophilic aromatic substitution (SNAr) is a direct method for arene functionalization; however, it can be hampered by low reactivity of arene substrates and their availability. Herein we describe a cation radical-accelerated nucleophilic aromatic substitution using methoxy- and benzyloxy-groups as nucleofuges. In particular, lignin-derived aromatics containing guaiacol and veratrole motifs were competent substrates for functionalization. We also demonstrate an example of site-selective substitutive oxygenation with trifluoroethanol to afford the desired trifluoromethylaryl ether.
Catalytic asymmetric protonation of α-amino acid-derived ketene disilyl acetals using P -Spiro diaminodioxaphosphonium barfates as chiral proton
Uraguchi, Daisuke,Kinoshita, Natsuko,Ooi, Takashi
supporting information; experimental part, p. 12240 - 12242 (2010/11/19)
Chiral diaminodioxaphosphonium salts have been developed and their unique abilities as a chiral proton have been revealed through the establishment of a highly enantioselective protonation of α-amino acid-derived ketene disilyl acetals.
