156685-94-8 Usage
Description
(2β,3α,5α)-21-chloro-3-hydroxy-2-(4-morpholinyl)pregnan-20-one is a synthetic steroid hormone that is structurally similar to the naturally-occurring hormone progesterone. It is characterized by a chlorine atom at the 21st position and a hydroxyl group at the 3rd position on the steroid backbone. Additionally, it contains a morpholine group attached to the 2nd carbon atom, which makes it a progesterone receptor agonist. Its chemical structure and pharmacological properties make it a subject of interest in the field of medicinal chemistry and drug development.
Uses
Used in Pharmaceutical Industry:
(2β,3α,5α)-21-chloro-3-hydroxy-2-(4-morpholinyl)pregnan-20-one is used as a pharmaceutical agent for the treatment of hormone-related cancers and gynecological disorders. Its agonistic effect on progesterone receptors makes it a potential therapeutic option for these conditions.
Used in Medicinal Chemistry Research:
(2β,3α,5α)-21-chloro-3-hydroxy-2-(4-morpholinyl)pregnan-20-one is used as a research compound in medicinal chemistry to study its structure-activity relationship and optimize its pharmacological properties for various therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 156685-94-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,6,8 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 156685-94:
(8*1)+(7*5)+(6*6)+(5*6)+(4*8)+(3*5)+(2*9)+(1*4)=178
178 % 10 = 8
So 156685-94-8 is a valid CAS Registry Number.
156685-94-8Relevant articles and documents
Anesthetic activity of novel water-soluble 2β-morpholinyl steroids and their modulatory effects at GABA(A) receptors
Anderson, Alison,Boyd, Andrew C.,Byford, Alan,Campbell, Alexander C.,Gemmell, David K.,Hamilton, Niall M.,Hill, David R.,Hill-Venning, Claire,Lambert, Jeremy J.,Maidment, Maurice S.,May, Valerie,Marshall, Richard J.,Peters, John A.,Rees, David C.,Stevenson, Donald,Sundaram, Hardy
, p. 1668 - 1681 (2007/10/03)
(3α,5α)-3-Hydroxypregnan-20-ones and (3α,5α)-3-hydroxypregnane- 11,20-diones bearing a 2β-morpholinyl substituent were synthesized, and the utility of these steroids as anesthetic agents was evaluated through determination of their potency and duration of
