156715-23-0 Usage
Description
1,5-Anhydro-4,6-O-Benzylidene-2-O-p-Toluoyl-D-Glucitol, also known as D-Glucitol, is a synthetic intermediate derived from sugar molecules. It is characterized by its white solid appearance and is widely used in the chemical and pharmaceutical industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
1,5-Anhydro-4,6-O-Benzylidene-2-O-p-Toluoyl-D-Glucitol is used as a synthetic intermediate for the preparation of sugar nucleotides, which are essential components in various biological processes and have potential applications in the development of new drugs and therapies.
Used in Chemical Industry:
1,5-Anhydro-4,6-O-Benzylidene-2-O-p-Toluoyl-D-Glucitol is used as a key building block in the synthesis of complex organic molecules, particularly in the field of carbohydrate chemistry. Its unique structure allows for further functionalization and modification, making it a valuable asset in the development of novel compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 156715-23-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,7,1 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 156715-23:
(8*1)+(7*5)+(6*6)+(5*7)+(4*1)+(3*5)+(2*2)+(1*3)=140
140 % 10 = 0
So 156715-23-0 is a valid CAS Registry Number.
156715-23-0Relevant articles and documents
Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides
Verheggen,Van Aerschot,Toppet,Snoeck,Janssen,Balzarini,De Clercq,Herdewijn
, p. 2033 - 2040 (1993)
The synthesis of 1,5-anhydrohexitol nucleosides is described. These nucleoside analogues were obtained by alkylation of the heterocyclic bases with the tosylate 10 or by alkylation of the bases with the alcohol 12 under Mitsunobu conditions. The compounds were evaluated for antiviral and cytostatic activity. Highly selective activity against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) was noted for 1,5-anhydro-2,3-dideoxy-2- (5-iodouracil-1-yl)-D-arabino-hexitol 4b at a concentration of 0.07 μg/mL. This activity must be dependent on a specific phosphorylation by the virus- encoded thymidine kinase (TK), since compound 4b was inactive against TK- deficient mutants of HSV-1. The corresponding cytosine 4c and guanine 4e analogues showed activity against HSV-1, HSV-2, and other herpes viruses (i.e. cytomegalovirus, varicella-zoster virus) at concentrations well below the cytotoxicity threshold (2 and 20 μg/mL, respectively). At these concentrations, compounds 4c and 4e proved also inhibitory to the growth of human T-cells (i.e. MT-4, CEM, MOLT-4).
