156767-69-0 Usage
Description
3beta-Hydroxyergost-5-en-7-one, also known as (24S)-3β-Hydroxyergost-5-en-7-one, is a secondary metabolite derived from the fruiting bodies of Cyttaria johowii. It is a derivative of Ergosterol (E599240), which is the most important of the provitamins D. Ergosterol is typically obtained from yeast and synthesized from simple sugars like glucose.
Uses
Used in Pharmaceutical Industry:
3beta-Hydroxyergost-5-en-7-one is used as an intermediate compound for the synthesis of various pharmaceutical products, including vitamins and other bioactive compounds. Its role in the synthesis process is crucial due to its structural similarity to Ergosterol, which is a key precursor in the production of vitamin D.
Used in Nutritional Supplements:
3beta-Hydroxyergost-5-en-7-one is used as a precursor in the development of nutritional supplements, particularly those focused on vitamin D enhancement. Its conversion to Ergosterol and subsequent conversion to vitamin D makes it a valuable component in the formulation of supplements aimed at improving bone health and immune function.
Used in Research and Development:
3beta-Hydroxyergost-5-en-7-one is utilized as a research compound for studying the structure, function, and potential applications of Ergosterol and its derivatives. This includes exploring its role in the synthesis of vitamin D and other bioactive compounds, as well as investigating its potential therapeutic uses in various health conditions.
Used in Cosmetics Industry:
3beta-Hydroxyergost-5-en-7-one may also be used in the cosmetics industry as an ingredient in the development of skincare products. Its potential benefits in promoting skin health and its connection to vitamin D synthesis could make it a valuable addition to products aimed at improving skin quality and overall health.
Check Digit Verification of cas no
The CAS Registry Mumber 156767-69-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,7,6 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 156767-69:
(8*1)+(7*5)+(6*6)+(5*7)+(4*6)+(3*7)+(2*6)+(1*9)=180
180 % 10 = 0
So 156767-69-0 is a valid CAS Registry Number.
156767-69-0Relevant articles and documents
Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells
O'Callaghan, Yvonne,Kenny, Olivia,O'Connell, Niamh M.,Maguire, Anita R.,McCarthy, Florence O.,O'Brien, Nora M.
, p. 496 - 503 (2013/04/24)
The cytotoxic effects of the oxidised derivatives of the phytosterols, stigmasterol and β-sitosterol, have previously been shown to be similar but less potent than those of the equivalent cholesterol oxides in the U937 cell line. The objective of the present study was to compare the cytotoxic effects of the oxidised derivatives of synthetic mixtures of campesterol and dihydrobrassicasterol in both the U937 and HepG2 cell lines. The parent compounds consisted of a campesterol: dihydrobrassicasterol mix at a ratio of 2:1 (2CMP:1DHB) and a dihydrobrassicasterol:campesterol mix at a ratio of 3:1 (3DHB:1CMP). The 2CMP:1DBH oxides were more cytotoxic in the U937 cells than the 3DBH:1CMP oxides but the difference in cytotoxicity was less marked in the HepG2 cells. The order of toxicity of the individual oxidation products was found to be similar to that previously observed for cholesterol, β-sitosterol and stigmasterol oxidation products in the U937 cell line. There was an increase in apoptotic nuclei in U937 cells incubated with the 7-keto and 7β-OH derivatives of both 2CMP:1DHB and 3DHB:1CMP and also in the presence of 3DHB:1CMP-3β,5α,6β-triol and 2CMP:1DHB-5β,6β-epoxide. An additional oxidation product synthesised from 2CMP:1DHB, 5,6,22,23-diepoxycampestane, was cytotoxic but did not induce apoptosis. These results signify the importance of campesterol oxides in the overall paradigm of phytosterol oxide cytotoxicity.
