1569453-21-9

Basic information

• Product Name: N-(but-3-en-1-yl)-4-chlorobenzamide
• Synonyms: N-(but-3-en-1-yl)-4-chlorobenzamide
• CAS NO: 1569453-21-9
• Molecular Weight: 209.675
• Mol File: 1569453-21-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(but-3-en-1-yl)-4-chlorobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(but-3-en-1-yl)-4-chlorobenzamide(1569453-21-9)
• EPA Substance Registry System: N-(but-3-en-1-yl)-4-chlorobenzamide(1569453-21-9)

Safety Data

• Hazardous Substances Data: 1569453-21-9(Hazardous Substances Data)

Upstream product

• 2524-49-4 3-butene-1-amine 
• 122-01-0 4-chloro-benzoyl chloride 
• 74-11-3 para-chlorobenzoic acid 
• 17875-18-2 but-3-en-1-amine hydrochloride 

Downstream Products

• 1569453-73-1 4-chloro-N-(3-chloro-5,5,5-trifluoropentyl)benzamide 

Relevant articles and documents

Iodoarene-catalyzed cyclizations of unsaturated amides

The cyclization of N-alkenylamides catalyzed by iodoarenes under oxidative conditions is presented. Five-, six-, and seven-membered rings with a range of substitutions can be prepared by this route. Preliminary data from the use of chiral iodoarenes as pr

Copper-Catalyzed Divergent Trifluoromethylation/Cyclization of Unactivated Alkenes

Most of the precedent copper-catalyzed trifluoromethylation reactions of unactivated alkenes concern terminal alkenes, and these processes are terminated in elimination, or nucleophilic addition, or semipinacol rearrangement, or C-H bond functionalization steps. In this study, we develop a trifluoromethylation method for both unactivated terminal and internal alkenes to enable divergent late-stage radical cyclization and achieve high molecular complexity. These cyclizations are well consistent with Baldwin's rule. Furthermore, a kinetic isotope effect (KIE) study and control reactions were conducted, and a plausible mechanism is proposed.