157064-68-1

Basic information

• Product Name: [3-Acetyl-1-(4-methoxy-phenyl)-2-methyl-1H-indol-5-yloxy]-acetic acid ethyl ester
• CAS NO: 157064-68-1
• Molecular Weight: 381.428
• Mol File: 157064-68-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [3-Acetyl-1-(4-methoxy-phenyl)-2-methyl-1H-indol-5-yloxy]-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [3-Acetyl-1-(4-methoxy-phenyl)-2-methyl-1H-indol-5-yloxy]-acetic acid ethyl ester(157064-68-1)
• EPA Substance Registry System: [3-Acetyl-1-(4-methoxy-phenyl)-2-methyl-1H-indol-5-yloxy]-acetic acid ethyl ester(157064-68-1)

Safety Data

• Hazardous Substances Data: 157064-68-1(Hazardous Substances Data)

Upstream product

• 5546-17-8 1-(p-Methoxyphenyl)-2-methyl-3-acetyl-5-oxyindole 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 157065-09-3 C₂₆H₂₃BrN₄O₃S 
• 157065-08-2 C₂₇H₂₆N₄O₄S 
• 157064-77-2 (3-Acetyl-6-bromo-2-methyl-1-phenyl-1H-indol-5-yloxy)-acetic acid hydrazide 
• 157064-76-1 [3-Acetyl-1-(4-methoxy-phenyl)-2-methyl-1H-indol-5-yloxy]-acetic acid hydrazide 

Relevant articles and documents

Biheterocycles: Synthesis and antimicrobial activity of 1',3',4'-oxadiazolyl/1'-pyrrolyl/1',2',4'-triazolylmethoxyindole derivatives

The chemoselectivity of C-5 ester over C-3 acetyl function towards the nucleophilic attack of hydrazine hydrate lead to the exclusive formation of substituted indol-5-yloxyacetic acid hydrazides (3a-h) from 5-ethoxycarbonylmethoxyindoles (2a-h).The acid hydrazides (3a-h) have been converted into the desired substituted 5-(5'-mercapto-1',3',4'-oxadiazol-2'-yl)methoxyindoles (5a-h), 5-(2',5'-dimethylpyrrol-1'-ylaminocarbonyl)methoxyindoles (6a-h) and 5-(4'-amino-5'-mercapto-1',2',4'-triazol-3'-yl)-methoxyindoles (7a-h).These acid hydrazides have also been converted intothe indol-5-ylomethylcarbothiosemicarbazides (8a-h) which on treatment with iodine-potassium iodide and sodium hydroxide give the desired 5-(5'-anilino-1',3',4'-oxadizol-2'-yl)-methoxyindoles and 5-(4'-phenyl-5'-mercapto-1',2',4'-triazol-3'-yl)-methoxyindoles respectively.Allthe newly synthesised compounds have been screened for their antibacterial and antifungal activities.