157068-00-3

Basic information

• Product Name: Ethanone, 2-bromo-1-(4-chloro-2-hydroxyphenyl)-
• CAS NO: 157068-00-3
• Molecular Formula: C8H6BrClO2
• Molecular Weight: 249.491
• Mol File: 157068-00-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-bromo-1-(4-chloro-2-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-bromo-1-(4-chloro-2-hydroxyphenyl)-(157068-00-3)
• EPA Substance Registry System: Ethanone, 2-bromo-1-(4-chloro-2-hydroxyphenyl)-(157068-00-3)

Safety Data

• Hazardous Substances Data: 157068-00-3(Hazardous Substances Data)

Usage

General Description

Ethanone, 2-bromo-1-(4-chloro-2-hydroxyphenyl)- is a chemical compound with the molecular formula C8H6BrClO2. It is a derivative of acetophenone with a bromine atom and a hydroxy group attached to the phenyl ring. Ethanone, 2-bromo-1-(4-chloro-2-hydroxyphenyl)- is commonly used in the synthesis of pharmaceuticals and organic compounds, and it has potential applications in the fields of medicine and biochemistry. Its specific properties and potential uses are of interest to researchers and chemical manufacturers looking to develop new materials and drugs.

Upstream product

• 6921-66-0 4-chloro-2-hydroxy acetophenone 

Downstream Products

• 402929-55-9 1-(4-chloro-2-hydroxyphenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone 
• 402929-57-1 1-(4-chloro-2-hydroxyphenyl)-2-(4H-1,2,4-triazol-4-yl)ethanone 
• 80930-53-6 1-(4-chloro-2-hydroxy-phenyl)-2-imidazol-1-yl-ethanone 
• 1315362-39-0 2-azido-1-(4-chloro-2-hydroxyphenyl)ethanone 
• 3260-78-4 6-chlorobenzofuran-3(2H)-one 

Relevant articles and documents

3-Hydroxychromone structure-based Raf kinase inhibitor, and preparation method and use thereof

The invention relates to the field of pharmaceutical chemistry, and concretely relates to 3-hydroxychromone compounds (A). R1-R9, X1 and X2 in the compounds (A) are as defined in the description. The invention also discloses preparation methods of the compounds represented by general formula (A), a medicinal composition containing the compounds, and a medicinal use of the compounds, especially a use of the compounds as a Raf kinase inhibitor and a tumor inhibitor.

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Compounds of formula (I): wherein c, X, Y, R2, R4 and R5 are defined herein, are useful as inhibitors of HIV replication.

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Compounds of formula I : wherein c, R2, R3, R4, R5, R6, R7 and R8 are defined herein, are useful as inhibitors of HIV replication.