15719-09-2Relevant articles and documents
Synthesis of Barbaralones and Bullvalenes Made Easy by Gold Catalysis
Ferrer, Sofia,Echavarren, Antonio M.
, p. 11178 - 11182 (2016/10/13)
The gold(I)-catalyzed oxidative cyclization of 7-ethynyl-1,3,5-cycloheptatrienes gives 1-substituted barbaralones in a general manner, which simplifies the access to other fluxional molecules. As an example, we report the shortest syntheses of bullvalene, phenylbullvalene, and disubstituted bullvalenes, and a readily accessible route to complex cage-type structures by further gold(I)-catalyzed reactions.