157368-88-2

Basic information

• Product Name: N,N'-Di(4-methylphenyl)oxalamidine
• Synonyms: N,N'-Di(4-methylphenyl)oxalamidine
• CAS NO: 157368-88-2
• Molecular Weight: 266.346
• Mol File: 157368-88-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N'-Di(4-methylphenyl)oxalamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-Di(4-methylphenyl)oxalamidine(157368-88-2)
• EPA Substance Registry System: N,N'-Di(4-methylphenyl)oxalamidine(157368-88-2)

Safety Data

• Hazardous Substances Data: 157368-88-2(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 460-19-5 ethanedinitrile 
• 106-49-0 p-toluidine 
• 7472-70-0 N,N'-bis(4-methylphenyl)ethanediimidoyl dichloride 
• 78-90-0 1,2-diaminopropan 
• 2074-87-5 carbon nitride 

Downstream Products

• 2580-79-2 diaminoglyoxime 
• 3299-61-4 N,N'-Di-p-tolyloxalamide 
• 42868-90-6 p-tolyl-oxalamide 
• 463-56-9 thiocyanic acid 
• 622-59-3 1-isothiocyanato-4-methylbenzene 
• 7664-41-7 ammonia 
• 106-49-0 p-toluidine 
• 200510-95-8 [5-(4-Methylphenylamino)-4-(4-methylphenylimino)-4H-imidazol-2-yl]-benzene 

Relevant articles and documents

Bis-amidines as useful building blocks for heterofulvenes and -fulvalenes

An easily feasible synthesis for bis-amidines of type 3 was developed via an aminolysis reaction of imidoyl chlorides 1 with gaseous ammonia. Depending on the nature of the electrophilic cyclization reagent, these amidines show a different reactivity. On treatment with orthoesters, the fused imidazoles 5 were obtained which involved the participation of two different kinds of nitrogen atoms in the cyclization. In contrast to this, carboxylic acid chlorides are able to react selectively at the NH2-groups under formation of the fulvenoid 4H-imidazoles 6. The same regioselectivity was observed for chlorodimethylimmonium chloride thus leading, via the dimerization of cyclic orthoamides, to the 1,4,5,8-tetraazafulvalenes 8.