1575-36-6

Basic information

• Product Name: 3-Bromo-1,2-diaminobenzene
• Synonyms: 1,2-Diamino-3-bromobenzene;3-Bromobenzene-1,2-diamine;3-Bromobenzene-1,2-diamine 97%;3-Bromophenylene-1,2-diamine;3-broMobenzene-1;2-AMino-3-broMoaniline;3-BroMo-o-phenylenediaMine;1,2-BenzenediaMine,3-broMo-
• CAS NO: 1575-36-6
• Molecular Formula: C₆H₇BrN₂
• Molecular Weight: 187.05
• EINECS: 1533716-785-6
• Mol File: 1575-36-6.mol
• Article Data: 17

Chemical Properties

• Melting Point: 125-126 °C
• Boiling Point: 290.441 °C at 760 mmHg
• Flash Point: 129.454 °C
• Appearance: /
• Density: 1.698 g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.696
• Storage Temp.: Room temperature.
• PKA: 3.09±0.10(Predicted)
• CAS DataBase Reference: 3-Bromo-1,2-diaminobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-1,2-diaminobenzene(1575-36-6)
• EPA Substance Registry System: 3-Bromo-1,2-diaminobenzene(1575-36-6)

Safety Data

• Statements: 43
• Safety Statements: 36/37
• Hazardous Substances Data: 1575-36-6(Hazardous Substances Data)

Usage

Description

3-Bromo-1,2-diaminobenzene is an organic compound with the molecular formula C6H7BrN2. It is characterized by the presence of a bromine atom at the 3-position and two amino groups at the 1 and 2 positions of a benzene ring. 3-Bromo-1,2-diaminobenzene is known for its potential applications in various fields due to its unique chemical structure and properties.

Uses

Used in Pharmaceutical Industry:
3-Bromo-1,2-diaminobenzene is used as a chemical intermediate for the synthesis of isomeric bromo analogues of Benzo-1H-triazole. These analogues have potential applications as inhibitors of protein kinases, which are important targets for the development of new drugs to treat various diseases, including cancer and inflammatory disorders.
In the pharmaceutical industry, 3-Bromo-1,2-diaminobenzene plays a crucial role in the development of novel therapeutic agents by providing a structural framework for the design and synthesis of new compounds with improved biological activities and selectivity. The compound's unique chemical properties, such as the presence of a bromine atom and amino groups, make it an attractive starting material for the synthesis of various bioactive molecules.
Furthermore, 3-Bromo-1,2-diaminobenzene can also be used in the development of new drug delivery systems, as its chemical structure allows for the attachment of various functional groups and moieties that can enhance the solubility, stability, and bioavailability of the resulting compounds. This can lead to the development of more effective and safer drugs with improved pharmacokinetic and pharmacodynamic properties.

InChI:InChI=1/C6H7BrN2/c7-4-2-1-3-5(8)6(4)9/h1-3H,8-9H2

Upstream product

• 19613-76-4 1-bromo-2,3-dinitro-benzene 
• 59255-95-7 2-bromo-6-nitroaniline 
• 22034-13-5 4-Bromo-benzo[1,2,5]thiadiazole 
• 273-13-2 benzo[1,2,5]thiadiazole 
• 95-54-5 1,2-diamino-benzene 
• 7138-15-0 3-bromo-2-nitrophenylamine 
• 591-19-5 m-Bromoaniline 

Downstream Products

• 83741-35-9 4-bromo-1H-benzo[d]imidazole 
• 20223-87-4 4-bromo-2-methyl-1H-benzo[d]imidazole 
• 207744-36-3 4-Bromo-1-(4-tert-butyl-benzyl)-2-methyl-1H-benzoimidazole 
• 207744-37-4 [1-(4-tert-Butyl-benzyl)-2-methyl-1H-benzoimidazol-4-yl]-phenyl-phosphinic acid ethyl ester 
• 207744-41-0 C₃₉H₄₂Br₂N₄ 
• 207744-38-5 4,4'-Dibromo-1,1'-bis-(3,5-di-tert-butyl-benzyl)-1H,1'H-[2,2']bibenzoimidazolyl 
• 207744-42-1 C₅₅H₆₂N₄O₄P₂ 
• 207744-39-6 C₆₀H₇₂N₄O₄P₂ 
• 180127-86-0 1,1'-Dibenzyl-4,4'-dibromo-1H,1'H-[2,2']bibenzoimidazolyl 
• 180127-84-8 4,4'-Dibromo-1,1'-bis-(4-tert-butyl-benzyl)-1H,1'H-[2,2']bibenzoimidazolyl 
• 180127-81-5 4,4'-Dibromo-1,1'-bis-(4-dodecyl-benzyl)-1H,1'H-[2,2']bibenzoimidazolyl 
• 928387-76-2 C₁₄H₁₇BrN₂O 
• 928387-74-0 C₁₄H₁₇BrN₂O 
• 40644-16-4 4‐bromo‐1,3‐dihydrobenzoimidazol‐2‐one 

Relevant articles and documents

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