157542-41-1

Basic information

• Product Name: 4-Penten-2-ol, 3-methyl-1-(phenylmethoxy)-, (2S,3R)-
• CAS NO: 157542-41-1
• Molecular Formula: C13H18O2
• Molecular Weight: 206.285
• Mol File: 157542-41-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-Penten-2-ol, 3-methyl-1-(phenylmethoxy)-, (2S,3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Penten-2-ol, 3-methyl-1-(phenylmethoxy)-, (2S,3R)-(157542-41-1)
• EPA Substance Registry System: 4-Penten-2-ol, 3-methyl-1-(phenylmethoxy)-, (2S,3R)-(157542-41-1)

Safety Data

• Hazardous Substances Data: 157542-41-1(Hazardous Substances Data)

Upstream product

• 590-18-1 (Z)-2-Butene 
• 60656-87-3 benzyloxyacetoaldehyde 
• 18147-55-2 but-2-enyltrichlorosilane 
• 18147-55-2 (Z)-crotyltrichlorosilane 
• 804559-38-4 (R,R)-crotylsilane 
• 100-39-0 benzyl bromide 
• 14593-43-2 benzyl allyl ether 
• 99397-92-9 (Z)-(-)-crotylbis(isopinocampheyl)borane 
• 197246-49-4 (3R,4S)-4-[[(1,1-dimethylethyl)dimethylsilyl]-oxy]-3-methyl-5-phenylmethoxy-1-pentene 

Downstream Products

• 180592-84-1 C₂₀H₂₄O₂ 
• 197246-49-4 (3R,4S)-4-[[(1,1-dimethylethyl)dimethylsilyl]-oxy]-3-methyl-5-phenylmethoxy-1-pentene 
• 677752-48-6 ((1S,2R)-1-Benzyloxymethyl-2-methyl-but-3-ynyloxy)-triethyl-silane 
• 677752-47-5 [2-((2R,3S,6S,8S,9R)-8-Benzyloxymethyl-3,9-dimethyl-1,7-dioxa-spiro[5.5]undec-2-yl)-ethoxy]-tert-butyl-dimethyl-silane 
• 677752-52-2 (2S,3R,9S,10R)-1-Benzyloxy-12-(tert-butyl-dimethyl-silanyloxy)-3,9-dimethyl-2,10-bis-triethylsilanyloxy-dodecan-6-one 
• 330573-62-1 (2R,3S)-3,4-Bis-benzyloxy-2-methyl-butan-1-ol 
• 330573-63-2 (3R,4S)-4,5-Bis-benzyloxy-3-methyl-pentane-1,2-diol 
• 157427-38-8 (2S,3S)-3,4-Bis-benzyloxy-2-methyl-butyraldehyde 
• 197246-52-9 (2S,3R,4S)-4-[[(1,1-dimethylethyl)dimethylsilyl]-oxy]-5-phenylmethoxy-3-methylpentane-1,2-diol 
• 197246-51-8 (2R,3R,4S)-4-[[(1,1-dimethylethyl)dimethylsilyl]-oxy]-5-phenylmethoxy-3-methylpentane-1,2-diol 
• 197246-57-4 [4S,6R,11R,4'S,1R,2S,1'E]-2,2-dimethyl-11-[2,4-dimethyl-5-[(tert-butyldimethylsilyl)oxy]-1-pentenyl]-4-[1-methyl-2-[(tert-butyldimethylsilyl)oxy]-3-phenylmethoxy-propyl]-1,3,7-trioxaspiroundecan-9-one 

Relevant articles and documents

A new and more powerfully activating diamine for practical and scalable enantioselective aldehyde crotylsilylation reactions

A new diaminophenol ligand for crotylsilylation reactions with cis- and trans-crotyltrichlorosilane has been developed. The conformational constraints that result from the tethering of the phenol to one of the amino groups attenuate the stereoelectronic effects that reduce activity in the corresponding untethered diaminosilanes, and the resulting crotylsilane reagents are as active as our previously reported EZ-CrotylMix reagents, but without requiring the use of the Sc(OTf)3 catalyst. In turn, this has allowed the development of an experimentally straightforward, sustainable, efficient, and scalable one-pot procedure which may be carried out in ≤8 hours, and in which the diaminophenol activator ligand may be easily recovered in ≥90% yield by recrystallization.

A more comprehensive and highly practical solution to enantioselective aldehyde crotylation

The enantioselective crotylation of aldehydes with 1,2- diaminochlorocrotylsilane reagents is effectively catalyzed by Sc(OTf) 3. The one significant limitation on the utility of these reagents-substrate scope-has thus been addressed. The net r

Toward creation of a universal NMR database for stereochemical assignment: Complete structure of the desertomycin/oasomycin class of natural products [10]

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