1576-38-1

Basic information

• Product Name: Benzenesulfonamide,4-methyl-N-(3-nitrophenyl)-
• Synonyms: p-Toluenesulfonanilide,3'-nitro- (7CI,8CI); 4-Methyl-3'-nitrobenzenesulfonanilide;4-methyl-N-(3-nitrophenyl)benzenesulfonamide; N-Tosyl-m-nitroaniline; NSC86602; m-Nitro-N-tosylaniline
• CAS NO: 1576-38-1
• Molecular Formula: C13H12 N2 O4 S
• Molecular Weight: 292.315
• Mol File: 1576-38-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide,4-methyl-N-(3-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide,4-methyl-N-(3-nitrophenyl)-(1576-38-1)
• EPA Substance Registry System: Benzenesulfonamide,4-methyl-N-(3-nitrophenyl)-(1576-38-1)

Safety Data

• Hazardous Substances Data: 1576-38-1(Hazardous Substances Data)

Upstream product

• 21849-40-1 dibromamine-T 
• 13331-27-6 m-nitrobenzene boronic acid 
• 645-00-1 m-iodonitrobenzene 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 6380-15-0 m-nitro-N-methyl-N-tosylaniline 
• 82670-10-8 N-methyl-N-tosyl-m-phenylenediamine 
• 16091-26-2 N-Benzoyl-m-phenylendiamin 
• 1253375-16-4 4-methyl-N-(3-nitrophenyl)-N-vinyl-benzenesulfonamide 
• 860752-97-2 toluene-4-sulfonic acid-(3-hydroxyamino-N-methyl-anilide) 
• 104-15-4 toluene-4-sulfonic acid 
• 121086-17-7 N-cyclohexyl-3-nitrobenzenamine 
• 4319-20-4 N-isopropyl-m-nitroaniline 
• 6380-07-0 N-(3-aminophenyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

CuI catalyzed sulfamidation of arylboronic acid using TsNBr2 at room temperature

An expeditious protocol for amidation arylboronic acid has been developed using TsNBr2 as the nitrogen source in presence of a CuI as catalyst. Various arylboronic acids could be transformed into corresponding N-arylsulfonamide derivatives within a very short time using CuI as catalyst in presence of DBU at room temperature.

Efficient ligand-free, copper-catalyzed N-arylation of sulfonamides

An efficient and convenient protocol has been developed for the N-arylation of sulfonamides with differently substituted aryl iodides using ligand-free copper iodide to afford the arylated products in good to excellent yields (up to 91%). Georg Thieme Verlag Stuttgart.