15764-16-6 Usage
Description
2,4-Dimethylbenzaldehyde, an isomer of dimethylbenzaldehyde, is a clear colorless liquid with a mild, sweet, and bitter-almond odor. It is characterized by its naphthyl, cherry, almond, spice, and vanilla taste at 20 ppm. 2,4-Dimethylbenzaldehyde is found in various natural sources such as cognac, brandy, black tea, grape, juniper berry, and clam.
Uses
Used in Flavor and Fragrance Industry:
2,4-Dimethylbenzaldehyde is used as a flavoring agent for its distinct naphthyl, cherry, almond, spice, and vanilla taste characteristics. Its ability to impart these flavors makes it a valuable addition to the flavor and fragrance industry.
Used in Pharmaceutical Industry:
2,4-Dimethylbenzaldehyde serves as a pharmacological intermediate, playing a crucial role in the synthesis of various drugs and medicinal compounds. Its chemical properties make it a versatile building block for creating new pharmaceuticals.
Used in Chemical Synthesis:
As a clear colorless liquid with a mild, sweet, and bitter-almond odor, 2,4-Dimethylbenzaldehyde can be utilized in chemical synthesis for creating a wide range of products, including specialty chemicals and additives.
Manufacturing Process:
2,4-Dimethylbenzaldehyde can be manufactured through the reaction between m-xylene and CO under the catalysis of powdery and anhydrous AlCl3, providing a reliable method for producing this valuable compound.
References
Yu-Long, W. U. "Study on the Synthesizing of 2,4-Dimethylbenzaldehyde." Chemical Intermediates (2008).
Yu-Long, W. U. "Study on Reaction Mechanism of Carbonylating Synthesis of 2,4-Dimethylbenzaldehyde from Meta-xylene." Technology & Development of Chemical Industry (2011).
Spicer, By, and V. Denise. "The effects of protein concentration and temperature on flavor delivery and volatility of 2,4-Dimethylbenzaldehyde and Ethyl butyrate in whey protein isolate solutions."
Preparation
By passing HCl into a mixture of o-xylole, aluminum chloride, sodium cyanide at 100°C.
Check Digit Verification of cas no
The CAS Registry Mumber 15764-16-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,7,6 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 15764-16:
(7*1)+(6*5)+(5*7)+(4*6)+(3*4)+(2*1)+(1*6)=116
116 % 10 = 6
So 15764-16-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O/c1-7-3-4-9(6-10)8(2)5-7/h3-6H,1-2H3
15764-16-6Relevant articles and documents
Influence of Protonation on Gattermann-Koch Formylation Rate of Alkylbenzene in CF3SO3H-SbF5
Tanaka, Mutsuo,Fujiwara, Masahiro,Ando, Hisanori
, p. 2106 - 2111 (1995)
The influence of the protonation on Gattermann-Koch formylation rate of alkylbenzenes was studied in CF3SO3H-SbF5.From the kinetic study of m-xylene formylation using various SbF5:m-xylene molar ratios in CF3SO3H, it is revealed that the formylation rate is explained with the equations which take into account the protonation equilibrium of m-xylene, and the apparent formylation rate is decreased by the protonation.The decrease of the apparent formylation rate by the protonation is proportional to the ratio of protonated alkylbenzene to form the ?-complex; therefore, the apparent relative formylation rate of alkylbenzenes is not consistent with their relative basicity under strong acidic conditions such as in CF3SO3H-SbF5.
A Transition-Metal-Free One-Pot Cascade Process for Transformation of Primary Alcohols (RCH2OH) to Nitriles (RCN) Mediated by SO2F2
Jiang, Ying,Sun, Bing,Fang, Wan-Yin,Qin, Hua-Li
supporting information, p. 3190 - 3194 (2019/05/21)
A new transition-metal-free one-pot cascade process for the direct conversion of alcohols to nitriles was developed without introducing an “additional carbon atom”. This protocol allows transformations of readily available, inexpensive, and abundant alcohols to highly valuable nitriles.
Simple formylation of aromatic compounds using a sodium formate/triphenylphosphine ditriflate system
Khodaei, Mohammad M.,Alizadeh, Abdolhamid,Hezarkhani, Hadis Afshar
supporting information, p. 840 - 843 (2017/06/13)
A new procedure was developed for formylation of arenes to produce aromatic aldehydes using a sodium formate/triphenylphosphine ditriflate system in ethanol at room temperature in good yields. The simplicity of the procedure, short reaction times, and mild reaction conditions are the other advantages of this metal- and carbon monoxide-free protocol.