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15769-56-9

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15769-56-9 Usage

Description

Gluronic acid is a sugar acid derived from glucose, with its sixth carbon atom oxidized to a carboxylic acid. It can exist in various forms, including linear and cyclic hemiacetal structures, and has two stereoisomers (Dand L-glucuronic acid) and two anomers (αand β-form) depending on its configuration at specific carbon atoms.

Uses

Used in Pharmaceutical Industry:
Gluronic acid is used as a key component in the synthesis of various drugs and pharmaceutical compounds due to its unique chemical properties and ability to form complexes with other molecules.
Used in Detoxification Processes:
Gluronic acid plays a crucial role in the detoxification processes within living organisms, as it helps in the conjugation and elimination of harmful substances, such as drugs and toxins, from the body.
Used in Food Industry:
Gluronic acid is used as an additive in the food industry for its emulsifying, stabilizing, and thickening properties, which contribute to the texture and shelf life of various products.
Used in Cosmetics Industry:
Gluronic acid is utilized in the cosmetics industry for its moisturizing and skin-conditioning properties, making it a valuable ingredient in skincare and personal care products.
Used in Research and Development:
Gluronic acid is employed in research and development for its potential applications in drug delivery systems, biomaterials, and other innovative technologies, due to its unique structural and functional characteristics.

Check Digit Verification of cas no

The CAS Registry Mumber 15769-56-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,7,6 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 15769-56:
(7*1)+(6*5)+(5*7)+(4*6)+(3*9)+(2*5)+(1*6)=139
139 % 10 = 9
So 15769-56-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h1-5,8-11H,(H,12,13)/t2-,3-,4+,5-/m0/s1

15769-56-9Related news

Preparation and characterization of guluronic acid (cas 15769-56-9) oligosaccharides degraded by a rapid microwave irradiation method09/26/2019

Guluronic acid oligosaccharides (GOS) with degree of polymerization (DP) ranging from 1 to 10 were prepared by a rapid microwave degradation method. Polyguluronic acid, fractionated from alginate hydrolysate, was dissolved in dilute ammonia water at a concentration of 20 mg/mL (pH 5) and then hy...detailed

An in vitro evaluation of anti-aging effect of guluronic acid (cas 15769-56-9) (G2013) based on enzymatic oxidative stress gene expression using healthy individuals PBMCs09/25/2019

BackgroundAging is usually associated with increased levels of oxidants, and may result in damages caused by oxidative stress. There is a direct relationship between aging and increased incidence of inflammatory diseases. The present research intended to study the anti-aging and anti-inflammator...detailed

Physicochemical properties of alginate-based films: Effect of ionic crosslinking and mannuronic and guluronic acid (cas 15769-56-9) ratio09/09/2019

The use of alginates as films in food applications has increased in the recent years due to their swelling capacity and overall functionality. This behaviour is a result of their capacity to crosslink with Ca2+ ion. Aiming to fully understand the effect of calcium chloride (CaCl2) crosslinking a...detailed

Impact of hydrolysis conditions on the detection of mannuronic to guluronic acid (cas 15769-56-9) ratio in alginate and its derivatives09/08/2019

Alginate is a linear and acidic polysaccharide, composed of (1 → 4) linked β-d-mannuronic acid (ManA) and α-l-guluronic acid (GulA). The ratio of ManA to GulA (M/G) is one of the most important factors for the application of alginate and its derivatives in various areas. In this work, a robus...detailed

Effects of guluronic acid (cas 15769-56-9) (G2013) on SHIP1, SOCS1 induction and related molecules in TLR4 signaling pathway09/07/2019

ObjectiveThis research aimed to study the anti-inflammatory and immunomodulatory effects of guluronic acid (G2013) on gene expression of TLR4, MyD88, SHIP1, SOCS1, NF-κB, and assessment of the level of IL-1β as a pro-inflammatory cytokine in HEK-Blue hTLR4 cell line.detailed

The alginate lyase from Isoptericola halotolerans CGMCC 5336 as a new tool for the production of alginate oligosaccharides with guluronic acid (cas 15769-56-9) as reducing end09/06/2019

Alginate oligosaccharides are depolymerization products of alginate by enzymatic degradation or physicochemical treatments. Alginate lyase has received great interests due to its use in oligosaccharide preparation. The substrate specificity of alginate lyase directly determines the type and degr...detailed

Original articleThe safety and efficacy of guluronic acid (cas 15769-56-9) (G2013) in ankylosing spondylitis: A randomized controlled parallel clinical trial09/05/2019

BackgroundTo assess the therapeutic efficacy, safety and tolerability of Guluronic acid (G2013) in patients with ankylosing spondylitis (AS) patients.detailed

15769-56-9Relevant articles and documents

Characterization of ulvan extracts to assess the effect of different steps in the extraction procedure

Costa, Carina,Alves, Anabela,Pinto, Paula R.,Sousa, Rui A.,Borges Da Silva, Eduardo A.,Reis, Rui L.,Rodrigues, Alírio E.

experimental part, p. 537 - 546 (2012/06/15)

An effective application development of the polysaccharide ulvan requires a comprehensive knowledge about the influence of the extraction process on composition of the extracts and in ulvan itself. In this context, the two main objectives of the present work are (1) the establishment of an efficient extraction process for ulvan and (2) development of an accurate characterization methodology to evaluate the extract composition and ulvan content. Three ulvan-rich extracts obtained by different schemes of extraction were studied. The methodology for the analysis was improved and a detailed analysis of extracted ulvan was provided. The polysaccharide is rich in ulvanobiuronic acid 3-sulfate type A [→4)-β-d-GlcAp-(1 → 4)-α-l-Rhap 3S-(1→], with minor amounts of ulvanobiuronic acid 3-sulfate type B [→4)-α-l-IdoAp-(1 → 4)-α-l-Rhap 3S-(1→]. The extract with the higher degree of purification is a high molecular weight polysaccharide (790 kDa) composed of rhamnose (22.4%), glucuronic acid (22.5%), xylose (3.7%), iduronic acid (3.1%) and glucose (1.0%). It is highly sulfated (32.2%) and contains 1.3% of proteins and 10.3% of inorganic material. Applying simple extraction scheme it was possible to obtain an extract from green algae with high content of ulvan without affecting the overall chemical structure of the polysaccharide.

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