1578-78-5

Basic information

• Product Name: α-fluoro-α-phenylmalonic acid
• Synonyms: α-fluoro-α-phenylmalonic acid
• CAS NO: 1578-78-5
• Molecular Weight: 198.151
• Mol File: 1578-78-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-fluoro-α-phenylmalonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: α-fluoro-α-phenylmalonic acid(1578-78-5)
• EPA Substance Registry System: α-fluoro-α-phenylmalonic acid(1578-78-5)

Safety Data

• Hazardous Substances Data: 1578-78-5(Hazardous Substances Data)

Upstream product

• 2802-98-4 diethyl 2-fluoro-2-phenylmalonate 
• 4870-65-9 2-bromophenylacetic acid 
• 83-13-6 diethyl 2-phenylmalonate 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 643-77-6 fluoro-phenyl-acetic acid ethyl ester 

Relevant articles and documents

Microbial asymmetric decarboxylation of fluorine-containing arylmalonic acid derivatives

α-Methyl-α-(trifluoromethylphenyl)malonic acids have been incubated with Alcaligenes bronchisepticus to afford optically active α-arylpropionic acids.Generally, the chemical and optical yields of the reaction products were higher when the substituents on the aromatic ring were strongly electron-withdrawing.Decarboxylation of α-fluoro-α-phenylmalonic acid with the aid of the same bacterium afforded optically active α-fluoro-α-phenylacetic acid.