157808-71-4

Basic information

• Product Name: (5R,6S)-7-Oxo-6-((R)-1-triethylsilanyloxy-ethyl)-3-(4-trifluoromethyl-phenyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester
• CAS NO: 157808-71-4
• Molecular Weight: 590.672
• Mol File: 157808-71-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5R,6S)-7-Oxo-6-((R)-1-triethylsilanyloxy-ethyl)-3-(4-trifluoromethyl-phenyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (5R,6S)-7-Oxo-6-((R)-1-triethylsilanyloxy-ethyl)-3-(4-trifluoromethyl-phenyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(157808-71-4)
• EPA Substance Registry System: (5R,6S)-7-Oxo-6-((R)-1-triethylsilanyloxy-ethyl)-3-(4-trifluoromethyl-phenyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(157808-71-4)

Safety Data

• Hazardous Substances Data: 157808-71-4(Hazardous Substances Data)

Upstream product

• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 79271-56-0 triethylsilyl trifluoromethyl sulfonate 
• 75363-99-4 4-nitrobenzyl (2R,5R,6S)-6-[(1R)-1-hydroxyethyl]-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate 

Relevant articles and documents

PREPARATION OF 2-ARYL- AND 2-ALKENYL-SUBSTITUTED CARBAPENEMS UNDER MILD SUZUKI CROSS-COUPLING CONDITIONS

An extraordinary mild procedure for the synthesis of 2-aryl- and 2-alkenyl-substituted carbapenems via palladium-catalyzed coupling of a vinyl triflate with aryl or vinyl boronic acids is described.A major advantage of this procedure is the use of nontoxic boronic acid intermediates in place of highly toxic organostannane compounds which are used in the corresponding Stille cross-coupling reactions.