157869-07-3

Basic information

• Product Name: Cinnoline, 4-bromo-3-(4-methoxyphenyl)-
• CAS NO: 157869-07-3
• Molecular Formula: C15H11BrN2O
• Molecular Weight: 315.169
• Mol File: 157869-07-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cinnoline, 4-bromo-3-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cinnoline, 4-bromo-3-(4-methoxyphenyl)-(157869-07-3)
• EPA Substance Registry System: Cinnoline, 4-bromo-3-(4-methoxyphenyl)-(157869-07-3)

Safety Data

• Hazardous Substances Data: 157869-07-3(Hazardous Substances Data)

Upstream product

• 768-60-5 4-methoxyphenylacetylen 
• 615-43-0 2-iodophenylamine 
• 1262057-03-3 (E)-1-((2-((4-methoxyphenyl)ethynyl)phenyl)diazenyl)piperidine 
• 1262057-09-9 1-(2-iodophenyl)-2-(piperidin-1-yl)diazene 
• 157869-15-3 2-((4-methoxyphenyl)ethynyl)aniline 

Relevant articles and documents

Richter cyclization and co-cyclization reactions of triazene-masked diazonium ions

The conventional Richter cyclization involves diazotization of 2-alkynylanilines with HX (aq) (X = Br or Cl) and NaNO2, followed by spontaneous ring closure to give a mixture of 4-halocinnoline and 4-cinnolinone products. The different products

A convenient synthesis of 4-chloro- and 4-bromocinnolines from o- aminophenylacetylenes

4-Chlorocinnolines and 4-bromocinnolines have been obtained in fair to good yields by diazotation of o-aminophenylacetylenes with sodium nitrite and concentrated hydrochloric acid or hydrobromic acid at temperatures between 25 and 30°C.