157924-46-4

Basic information

• Product Name: 2,4-diamino-5-iodopyrimidine
• Synonyms: 2,4-diamino-5-iodopyrimidine
• CAS NO: 157924-46-4
• Molecular Weight: 236.015
• Mol File: 157924-46-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 212-214 °C(Solv: acetonitrile (75-05-8))
• Boiling Point: 447.7±55.0 °C(Predicted)
• Density: 2.302±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2,4-diamino-5-iodopyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-diamino-5-iodopyrimidine(157924-46-4)
• EPA Substance Registry System: 2,4-diamino-5-iodopyrimidine(157924-46-4)

Safety Data

• Hazardous Substances Data: 157924-46-4(Hazardous Substances Data)

Usage

General Description

2,4-diamino-5-iodopyrimidine, also known as 5-Iodo-DAP, is a chemical compound that belongs to the pyrimidine group. It is a derivative of 2,4-diamino pyrimidine and contains an iodine atom. 2,4-diamino-5-iodopyrimidine is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its versatility and ability to act as a building block for various chemical reactions. It also has potential applications in the field of medicinal chemistry and drug development, particularly in the creation of novel therapeutic agents. Additionally, 2,4-diamino-5-iodopyrimidine has been studied for its antimicrobial and antiparasitic properties, making it a promising candidate for the development of new drugs to combat infectious diseases.

Upstream product

• 156-81-0 2,4-diaminopyrimidine 

Downstream Products

• 1088496-59-6 2,4-diamino-5-[3-(2,5-dimethoxyphenyl)prop-1-ynyl]pyrimidine 
• 928618-11-5 5-[(3,4,5-trimethoxyphenyl)ethynyl]pyrimidine-2,4-diamine 

Relevant articles and documents

HETEROCYCLIC COMPOUND

Provided is a heterocyclic compound that may have a GCN2 inhibitory action, and is expected to be useful for the prophylaxis or treatment of GCN2 associated diseases including cancer and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

A convenient synthesis of N,N'-dibenzyl-2,4-diaminopyrimidine-2'- deoxyribonucleoside and 1-Methyl-2'-deoxypseudoisocytidine

The syntheses of N,N'-dibenzyl-2,4-diaminopyrimidine-2'-deoxyribonucleoside and 1-methyl-2'-deoxypseudoisocytidine via Heck coupling are described. A survey of the attempts to use the Heck coupling to synthesize N,N'-dibenzyl-2,4-diaminopyrimidine-2'-deox

Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis

The search for effective therapeutics for cryptosporidiosis and toxoplasmosis has led to the discovery of novel inhibitors of dihydrofolate reductase (DHFR) that possess high ligand efficiency: compounds with high potency and low molecular weight. Detaile