15793-94-9

Basic information

• Product Name: 1-(isoquinolin-1-yl)hydrazine
• Synonyms: 1-HYDRAZINOISOQUINOLINE;1-hydrazinoisoquinoline(SALTDATA: 1HBr 1H2O);1-hydrazinoisoquinoline hydrochloride;1-isoquinolylhydrazine;isoquinolin-1-ylhydrazine;MFCD11983589;1-(isoquinolin-1-yl)hydrazine
• CAS NO: 15793-94-9
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 159.19
• Mol File: 15793-94-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 143 °C
• Boiling Point: 400.507°C at 760 mmHg
• Flash Point: 196.02°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.758
• PKA: 7.57±0.20(Predicted)
• CAS DataBase Reference: 1-(isoquinolin-1-yl)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(isoquinolin-1-yl)hydrazine(15793-94-9)
• EPA Substance Registry System: 1-(isoquinolin-1-yl)hydrazine(15793-94-9)

Safety Data

• Hazardous Substances Data: 15793-94-9(Hazardous Substances Data)

Usage

General Description

1-(isoquinolin-1-yl)hydrazine is a chemical compound with the molecular formula C9H9N3. It is a hydrazine derivative with an isoquinoline group, which is a bicyclic structure consisting of a benzene ring fused to a pyridine ring. 1-(isoquinolin-1-yl)hydrazine is primarily used in the pharmaceutical industry as a building block for the synthesis of various bioactive molecules. It can also be used in the production of dyes and pigments. 1-(isoquinolin-1-yl)hydrazine has the potential to undergo various chemical reactions, making it a versatile intermediate in organic synthesis. Due to its chemical structure and potential reactivity, it is important to handle this compound with caution and in accordance with proper safety protocols.

InChI:InChI=1/C9H9N3/c10-12-9-8-4-2-1-3-7(8)5-6-11-9/h1-6H,10H2,(H,11,12)

Upstream product

• 119-65-3 isoquinoline 
• 19493-44-8 1-chloroisoquinoline 
• 491-30-5 1-hydroxyisoquinoline 
• 302-01-2 hydrazine 
• 491-30-5 1-isoquinolone 

Downstream Products

• 103837-20-3 N-Isoquinolin-1-yl-N'-[1-phenyl-1-pyridin-2-yl-meth-(Z)-ylidene]-hydrazine 
• 877403-00-4 tert-butyl [(1R)-1-(2,5-difluorobenzyl)-3-(2-isoquinolin-1-ylhydrazino)-3-oxopropyl]carbamate 
• 1448812-54-1 N-(3-chloro-5-(((4-cyano-1-(isoquinolin-1-yl)-3-methyl-1H-pyrazol-5-yl)amino)methyl)-2-hydroxyphenyl)propionamide 
• 3223-55-0 3-phenyl-[1,2,4]triazolo[3,4-a]isoquinoline 
• 2746-49-8 benzaldehyde isoquinolin-1-ylhydrazone 
• 440-54-0 s-Triazolo<3,4-a>isochinolin 
• 7639-56-7 3-Methyl-s-triazolo<3,4-a>isochinolin 

Relevant articles and documents

Synthesis of Some Isoquinolyl-1-hydrazones and Spectrophotometric Characterization of Some of Their Transition-Metal Chelates

Synthesis of 1-hydrazinoisoquinoline and nine of its hydrazones is reported together with spectrophotometric data from the visible spectral region for their chelates with iron(II), cobalt(II), nickel(II), and copper(II).

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.

PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS

This invention is directed to pyrazole and pyrrole compounds, for example, compounds of formula (I): wherein R1, R2, R3 and R4 are as defined herein, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of iron disorders. This invention is also directed to pharmaceutical compositions comprising the compounds and methods of using the compounds to treat iron disorders.