157945-01-2

Basic information

• Product Name: (S)-tert-butyl (3S,4R)-5-(benzyloxy)-3-hydroxy-4-methylpentanethioate
• Synonyms: (S)-tert-butyl (3S,4R)-5-(benzyloxy)-3-hydroxy-4-methylpentanethioate
• CAS NO: 157945-01-2
• Molecular Weight: 310.458
• Mol File: 157945-01-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl (3S,4R)-5-(benzyloxy)-3-hydroxy-4-methylpentanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl (3S,4R)-5-(benzyloxy)-3-hydroxy-4-methylpentanethioate(157945-01-2)
• EPA Substance Registry System: (S)-tert-butyl (3S,4R)-5-(benzyloxy)-3-hydroxy-4-methylpentanethioate(157945-01-2)

Safety Data

• Hazardous Substances Data: 157945-01-2(Hazardous Substances Data)

Upstream product

• 999-90-6 S-tert-butyl thioacetate 
• 79026-61-2 (R)-3-benzyloxy-2-methylpropanal 
• 121534-52-9 1-(tert-butyldimethylsiloxy)-1-(tert-butylsulfanyl)ethene 

Downstream Products

• 115508-75-3 (3S,4R)-5-(benzyloxy)-4-methylpentane-1,3-diol 

Relevant articles and documents

A practical synthesis of the C1-C9 fragment of dictyostatin

A stereoselective synthesis of the C1-C9 fragment of (-)-dictyostatin has been achieved by use of a titanium(IV) chloride mediated chelation-controlled Mukaiyama aldol reaction and two modified Horner-Wadsworth-Emmons olefinations (Roush-Masamune and Stil

Reagent control in the aldol addition reaction of chiral boron enolates with chiral aldehydes

Boron enolates bearing menthone-derived chiral ligands are capable of fair to excellent diastereocontrol in their reactions with chiral aldehydes. Thioester-derived (better than ketone derived) enolates are able to control aldol stereochemistry irrespective of the aldehyde preferences.