158-95-2 Usage
Molecular structure
1,4,7,10-Tetraoxadispiro[4.0.4.4]tetradecane has a unique and complex molecular structure, with two non-adjacent carbon atoms connected to the same atom, forming a spiro compound.
Tetraoxadispiro structure
The compound contains oxygen atoms in addition to carbon atoms, resulting in a tetraoxadispiro structure.
Type of hydrocarbon
It is a type of tetradecane, which refers to a hydrocarbon molecule with 14 carbon atoms.
Synthetic compound
1,4,7,10-Tetraoxadispiro[4.0.4.4]tetradecane is a synthetic compound, meaning it is created through chemical synthesis rather than being found naturally.
Potential applications
The compound has potential applications in the field of organic chemistry and materials science, although its specific uses and properties have yet to be fully explored and understood.
Molecular weight
The molecular weight of the compound is approximately 200.23 g/mol.
Physical properties
The specific physical properties of 1,4,7,10-Tetraoxadispiro[4.0.4.4]tetradecane, such as melting point, boiling point, and solubility, have not been fully documented.
Stability
As a synthetic compound, the stability of 1,4,7,10-Tetraoxadispiro[4.0.4.4]tetradecane under various conditions is not well-established.
Reactivity
The reactivity of 1,4,7,10-Tetraoxadispiro[4.0.4.4]tetradecane with other chemicals or under different conditions is not well-documented and requires further research.
Check Digit Verification of cas no
The CAS Registry Mumber 158-95-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,5 and 8 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 158-95:
(5*1)+(4*5)+(3*8)+(2*9)+(1*5)=72
72 % 10 = 2
So 158-95-2 is a valid CAS Registry Number.
158-95-2Relevant articles and documents
A novel strategy for the asymmetric synthesis of (S)-ketamine using (S)-tert-butanesulfinamide and 1,2-cyclohexanedione
Taghizadeh, Mohammad Javad,Gohari, Seyed Jamal Addin,Javidan, Abdollah,Moghimi, Abolghasem,Iman, Maryam
, p. 2175 - 2181 (2018/08/29)
Abstract: We present a novel asymmetric synthesis route for synthesis of (S)-ketamine?using a chiral reagent according to the strategy (Scheme 1), with good enantioselectivity (85% ee) and yield. In this procedure, the (S)-tert-butanesulfinamide (TBSA) acts as a chiral auxiliary reagent to generate (S)-ketamine. A series of new intermediates were synthesized and identified for the first time in this work (2–4). The monoketal intermediate (1) easily obtained after partial conversion of one ketone functional group of 1,2-cyclohexanedione into a ketal using ethylene glycol. The sulfinylimine (2) was obtained by condensation of (S)-tert-butanesulfinamide (TBSA) with (1), 4-dioxaspiro[4.5]decan-6-one in 90% yield. The (S)-N-tert-butanesulfinyl ketamine (3) was prepared on further reaction of sulfinylimine (2) with appropriate Grignard reagent (ArMgBr) in which generated chiral center in 85% yield and with 85% diastereoselectivity. Methylation of amine afforded the product (4). Finally, the sulfinyl- and ketal-protecting groups were removed from the compound (4) by brief treatment with stoichiometric quantities of HCl in a protic solvent gave the (S)-ketamine in near quantitative yield. Graphical abstract: [Figure not available: see fulltext.].
