15800-90-5

Basic information

• Product Name: 10-(2-hydroxyethyl)benzo[g]pteridine-2,4(3H,10H)-dione
• CAS NO: 15800-90-5
• Molecular Formula: C₁₂H₁₀N₄O₃
• Molecular Weight: 258.2328
• Mol File: 15800-90-5.mol
• Article Data: 4

Chemical Properties

• Density: 1.64g/cm³
• Refractive Index: 1.779
• CAS DataBase Reference: 10-(2-hydroxyethyl)benzo[g]pteridine-2,4(3H,10H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 10-(2-hydroxyethyl)benzo[g]pteridine-2,4(3H,10H)-dione(15800-90-5)
• EPA Substance Registry System: 10-(2-hydroxyethyl)benzo[g]pteridine-2,4(3H,10H)-dione(15800-90-5)

Safety Data

• Hazardous Substances Data: 15800-90-5(Hazardous Substances Data)

Usage

Chemical Family

Pteridine family

Physical State

Crystalline solid

Molecular Weight

302.31 g/mol

Applications

Pharmaceutical and medicine

Therapeutic Properties

Exhibits potential therapeutic properties

Research and Development

Used as a building block for the synthesis of various organic compounds

Disease Treatment

Studied for potential role in the treatment of certain diseases and medical conditions

Scientific Research

Important molecule in the field of scientific research and drug discovery

Chemical Structure

Contains a benzo[g]pteridine core with a 2-hydroxyethyl group at the 10th position and a 2,4-dione group.

Upstream product

• 4926-58-3 2-((2-hydroxyethyl)amino)aniline 
• 3237-50-1 5,5-dihydroxy-pyrimidine-2,4,6-trione 
• 4926-55-0 2-[(2-nitrophenyl)amino]ethanol 
• 577-19-5 2-nitrophenyl bromide 
• 61066-33-9 pyrimidine-2,4,5,6(1H,3H)-tetraone 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 490-59-5 alloxazine 
• 4074-58-2 10-methyl-isoalloxazine 
• 50-00-0 formaldehyd 
• 75-07-0 acetaldehyde 
• 114853-42-8 1,10-ethyleneisoalloxazinium chloride 

Relevant articles and documents

Robust Photocatalytic Method Using Ethylene-Bridged Flavinium Salts for the Aerobic Oxidation of Unactivated Benzylic Substrates

7,8-Dimethoxy-3-methyl-1,10-ethylenealloxazinium chloride (1a) was found to be a superior photooxidation catalyst among substituted ethylene-bridged flavinium salts (R=7,8-diMeO, 7,8-OCH2O-, 7,8-diMe, H, 7,8-diCl, 7-CF3 and 8-CF3). Selection was carried out based on structure vs catalytic activity and properties relationship investigations. Flavinium salt 1a proved to be robust enough for practical applications in benzylic oxidations/oxygenations, which was demonstrated using a series of substrates with high oxidation potential, i. e., 1-phenylethanol, ethylbenzene, diphenylmethane and diphenylmethanol derivatives substituted with electron-withdrawing groups (Cl or CF3). The unique capabilities of 1a can be attributed to its high photostability and participation via a relatively long-lived singlet excited state, which was confirmed using spectroscopic studies, electrochemical measurements and TD-DFT calculations. This allows the maximum use of the oxidation power of 1a, which is given by its singlet excited state reduction potential of +2.4 V. 7,8-Dichloro-3-methyl-1,10-ethylenealloxazinium chloride (1 h) can be used as an alternative photocatalyst for even more difficult substrates. (Figure presented.).

CHEMICAL REGENERATION METHOD OF OXIDIZED COENZYME NAD (P)+

It discloses a chemical regeneration method of oxidized coenzyme NAD(P)+ which is under an oxygen or air atmosphere condition, adding a catalytic amount of bridged flavin, and oxidizing NAD(P)H to obtain NAD(P)+. The catalyst for regeneration of cofactor is cheap and easily available small organic molecule having no noble metal; this regeneration system can regenerate NADH and NADPH; this regeneration system has a wide pH range and temperature range, being applicable to various oxidation reactions catalyzed by nicotinamide-dependent oxidoreductase.