1581258-00-5

Basic information

• Product Name: 5-(6-(2-(2,2-dimethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethylamino)pyrazin-2-yl)nicotinonitrile
• Synonyms: 5-(6-(2-(2,2-dimethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethylamino)pyrazin-2-yl)nicotinonitrile
• CAS NO: 1581258-00-5
• Molecular Weight: 413.522
• Mol File: 1581258-00-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(6-(2-(2,2-dimethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethylamino)pyrazin-2-yl)nicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(6-(2-(2,2-dimethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethylamino)pyrazin-2-yl)nicotinonitrile(1581258-00-5)
• EPA Substance Registry System: 5-(6-(2-(2,2-dimethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethylamino)pyrazin-2-yl)nicotinonitrile(1581258-00-5)

Safety Data

• Hazardous Substances Data: 1581258-00-5(Hazardous Substances Data)

Upstream product

• 1581258-29-8 6-chloro-N-(2-(2,2-dimethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethyl)pyrazin-2-amine 
• 497147-93-0 3-cyanopyridine-5-boronic acid 
• 126317-99-5 2-(2,2-dimethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethanamine 

Relevant articles and documents

TETRAHYDROPYRAN-4-YLETHYLAMINO- OR TETRAHYDROPYRANYL-4-ETHYLOXY-PYRIMIDINES OR -PYRIDAZINES AS ISOPRENYLCYSTEINCARBOXYMETHYL TRANSFERASE INHIBITORS

A compound of formula (I): wherein: R1 is selected from: (i) phenyl, optionally substituted by one fluoro group; (ii) thienyl; (iii) furanyl; (iv) C1-4 alkyl; and (v) H; R2 is selected from: (II), R3 is selected from: (III), X is selected from NH and O; R4 is selected from phenyl, a 5-membered heteroaryl or a 6-membered heteroaryl, all of which are optionally substituted by one or more substituents selected from the group consisting of: methyl, methoxy, trifluoromethyl, trifluoromethoxy, cyano, fluoro, -OC2H4OMe, and pyrazolyl.