1581709-78-5

Basic information

• Product Name: 2-(1-phenylvinyl)pyrimidine
• Synonyms: 2-(1-phenylvinyl)pyrimidine
• CAS NO: 1581709-78-5
• Molecular Weight: 182.225
• Mol File: 1581709-78-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(1-phenylvinyl)pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-phenylvinyl)pyrimidine(1581709-78-5)
• EPA Substance Registry System: 2-(1-phenylvinyl)pyrimidine(1581709-78-5)

Safety Data

• Hazardous Substances Data: 1581709-78-5(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 53342-27-1 2-acetylpyrimidine 
• 127-19-5 N,N-dimethyl acetamide 
• 90210-57-4 benzyl-pyrimidine 

Relevant articles and documents

Palladium-Catalyzed Divergent Arylation with Triazolopyridines: One-Pot Synthesis of 6-Aryl-2-α-styrylpyridines

We have developed a new strategy for palladium-catalyzed arylation reactions with triazolopyridines, wherein two different chemical transformations (C-3 vs. C-7) are observed by differentiating the substrates using different bases. The reactive palladium carbenoids were directly generated from triazolopyridines and underwent denitrogenative arylations with aryl bromides. Intriguingly, when potassium carbonate was replaced with potassium tert-butoxide, direct C-H arylation occurred at the most acidic position (C-7). Moreover, two different catalytic arylation events were successfully performed in a one-pot sequence, providing a convenient access to 6-aryl-2-α-styrylpyridines.