1581735-04-7 Usage
Description
(R)-2-((S)-1-tert-butoxy-3-cyclopropyl-1-oxopropan-2-yl)-5,5,5-trifluoropentanoic acid is a complex organic compound featuring a combination of (R)and (S)isomers, a tert-butoxy group, a cyclopropyl group, and a trifluoropentanoic acid group. The presence of these functional groups suggests potential applications in various industries, particularly due to the biological activity and metabolic stability enhancements provided by the fluorinated groups and the unique steric and conformational properties conferred by the cyclopropyl group.
Uses
Used in Pharmaceutical Industry:
(R)-2-((S)-1-tert-butoxy-3-cyclopropyl-1-oxopropan-2-yl)-5,5,5-trifluoropentanoic acid is used as a key intermediate in the synthesis of pharmaceutical compounds for various therapeutic applications. The presence of fluorinated groups can improve the compound's biological activity and metabolic stability, making it a valuable asset in drug design and discovery.
Used in Agrochemical Industry:
In the agrochemical industry, (R)-2-((S)-1-tert-butoxy-3-cyclopropyl-1-oxopropan-2-yl)-5,5,5-trifluoropentanoic acid is used as a building block for the development of novel agrochemicals, such as pesticides and herbicides. (R)-2-((S)-1-tert-butoxy-3-cyclopropyl-1-oxopropan-2-yl)-5,5,5-trifluoropentanoic acid's unique structure and functional groups can contribute to the creation of more effective and targeted agrochemical products.
Used in Chemical Research:
(R)-2-((S)-1-tert-butoxy-3-cyclopropyl-1-oxopropan-2-yl)-5,5,5-trifluoropentanoic acid serves as a versatile compound in chemical research, particularly in the study of stereochemistry and the development of new synthetic methods. Its complex structure and the presence of multiple functional groups make it an interesting subject for researchers to explore and understand its potential applications and reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1581735-04-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,8,1,7,3 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1581735-04:
(9*1)+(8*5)+(7*8)+(6*1)+(5*7)+(4*3)+(3*5)+(2*0)+(1*4)=177
177 % 10 = 7
So 1581735-04-7 is a valid CAS Registry Number.
1581735-04-7Relevant articles and documents
A Practical Approach for Enantio- and Diastereocontrol in the Synthesis of 2,3-Disubstituted Succinic Acid Esters: Synthesis of the pan-Notch Inhibitor BMS-906024
Quesnelle, Claude A.,Gill, Patrice,Kim, Soong-Hoon,Chen, Libing,Zhao, Yufen,Fink, Brian E.,Saulnier, Mark,Frennesson, David,DeMartino, Michael P.,Baran, Phil S.,Gavai, Ashvinikumar V.
, p. 2254 - 2258 (2016/10/19)
An oxidative intermolecular enolate heterocoupling reaction was employed for the synthesis of anti-2,3-disubstituted succinic acid mono- and differentially protected diesters. Tactical approaches to access all the diastereomers are discussed. The method w
TRICYCLIC HETEROCYCLIC COMPOUNDS AS NOTCH INHIBITORS
-
, (2014/04/04)
Disclosed are compounds of Formula (I), wherein: X is O or -NR3; R1 is -CH2CH2CH3, -CH2CF3, -CH2CH2CF3, -CH2CF2CH3, -CH2CH2CH2CF3, -CH2CH2CF2CH3, -CH2CH(CH3)CF3, -CH2CH2CH2F, or CH2(cyclopropyl); R2 is -CH2CH2CH3, -CH2CF3, -CH2CH2CF3, -CH2CF2CH3, -CH2CH2CH2CF3, -CH2CH2CH2F, -CH2CH(CH3)CF3, CH2CH2CF2CH3, -CH2(cyclopropyl), -CH(CH3)(cyclopropyl), phenyl, fluorophenyl, chlorophenyl, trifluorophenyl, methylisoxazolyl, pyridinyl, formula (i), formula (ii), formula (iii), formula (iv) or formula (v); Ring A is phenyl or pyridinyl; and R3, Ra, Rb, Rc, y, and z are defined herein. Also disclosed are methods of using such compounds to inhibit the Notch receptor, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as cancer.