1582-79-2 Usage
Description
3,5-Di-O-p-chlorobenzoyl Floxuridine is a chemical derivative of Floxuridine, a nucleoside analog used in cancer treatment. It is characterized by its white solid appearance and is designed to protect the Floxuridine molecule, enhancing its stability and efficacy in various applications.
Uses
Used in Pharmaceutical Industry:
3,5-Di-O-p-chlorobenzoyl Floxuridine is used as a protected form of Floxuridine for enhancing the drug's stability and bioavailability. The protection of Floxuridine by this compound aims to improve its effectiveness in cancer treatment by reducing degradation and increasing the drug's half-life in the body.
Additionally, 3,5-Di-O-p-chlorobenzoyl Floxuridine is used as a protected mixture of Floxuridine anomers, which can provide a more consistent and reliable therapeutic effect in cancer treatment. This approach ensures that the active pharmaceutical ingredient (API) is delivered in a more controlled and predictable manner, potentially leading to better patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 1582-79-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,8 and 2 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1582-79:
(6*1)+(5*5)+(4*8)+(3*2)+(2*7)+(1*9)=92
92 % 10 = 2
So 1582-79-2 is a valid CAS Registry Number.
1582-79-2Relevant articles and documents
FLOXURIDINE SYNTHESIS
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Page/Page column 32-33, (2019/04/11)
The present invention relates to a process for the preparation of floxuridine, said process comprising reacting a compound of Formula la with a compound of Formula lla in the presence of an acid Al to provide a compound of Formula Ilia in substantially diastereomerically pure form. Floxuridine may be useful as an anti-cancer drug. Floxuridine may also be useful in the preparation of other anti-cancer drugs, e.g. NUC-3373.
Stereoselective synthesis of the anomeric 5-mercapto-2'deoxyuridines and of some other alpha-and beta-deoxyribonucleosides.
Bardos,Kotick,Szantay
, p. 1759 - 1764 (2007/10/07)
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