15828-10-1

Basic information

• Product Name: 3-Pyridinecarbonitrile, 4-amino-1,2-dihydro-6-hydroxy-2-oxo-
• Synonyms: 3-Pyridinecarbonitrile, 4-amino-1,2-dihydro-6-hydroxy-2-oxo-;4-amino-2,6-dihydroxy-nicotinonitrile;4-amino-1,2-dihydro-6-hydroxy-2-oxo-3-Pyridinecarbonitrile
• CAS NO: 15828-10-1
• Molecular Formula: C6H5N3O2
• Molecular Weight: 151.12
• Mol File: 15828-10-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinecarbonitrile, 4-amino-1,2-dihydro-6-hydroxy-2-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 4-amino-1,2-dihydro-6-hydroxy-2-oxo-(15828-10-1)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 4-amino-1,2-dihydro-6-hydroxy-2-oxo-(15828-10-1)

Safety Data

• Hazardous Substances Data: 15828-10-1(Hazardous Substances Data)

Usage

General Description

"3-Pyridinecarbonitrile, 4-amino-1,2-dihydro-6-hydroxy-2-oxo-" is a chemical compound with the molecular formula C6H6N3O2. It is a derivative of pyridine and contains a nitrile functional group, as well as an amino, hydroxy, and oxo groups. 3-Pyridinecarbonitrile, 4-amino-1,2-dihydro-6-hydroxy-2-oxo- is commonly used in organic synthesis and pharmaceutical research due to its potential pharmacological activities and biological properties. It can be utilized as a building block in the synthesis of various pharmaceutical drugs and organic compounds, making it a valuable and versatile chemical in the field of chemistry and drug development.

Upstream product

• 110568-62-2 (Z)-3-Amino-4-carbamoyl-2-cyan-2-butensaeure-methylester 
• 78429-16-0 (Z)-3-Amino-2-cyan-2-pentendisaeure-dimethylester 
• 107-91-5 cyanoacetic acid amide 
• 102266-58-0 4-Amino-1,6-dihydro-2-methoxy-6-oxo-3-pyridincarbonitril 
• 86165-77-7 ethyl 3-amino-4,4-dicyanobut-3-enoate 

Downstream Products

• 5768-12-7 piperidine-2,4,6-trione 

Relevant articles and documents

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Syntheses with Nitriles, LXXIX. Methyl 3-Amino-4-carbomyl-2-cyano-2-butenoate, a Dimer of Methyl Cyanoacetate and Cyanoacetamide

Synthesis of methyl 3-amino-4-carbomyl-2-cyano-2-butenoate is described and 2a classified as a dimer of methyl cyanoacetate and cyanoacetamide.By ammonolysis of the dimer of methyl cyanoacetate with dimethylamine and anilines, resp. the dimethylamide and anilides, resp. (2b and 3a-j) are obtained.Condensation with salicylaldehyde to the pyrone derivative 4 proves the structure of 2a, ring closure reactions in basic or acidic medium yield the pyridones 6a and 7a,b, coupling with diazonium salts the pyridazines 8a-d.The amides 2 and the anilides 3 show hindered rotation of the enamino- and the amide-group by hydrogen bonds between the nitrogen functions and the ester carbonyl (Z-form).The ΔG(excit.) values are reported. - Keywords: Cyanoacetate; Cyanoacetamide; Dimer