1583286-47-8 Usage
Type of compound
Boronic ester derivative It is derived from a boronic acid and an alcohol, resulting in a compound with a boron atom bonded to two oxygen atoms.
Boron atom
Bonded to two oxygen atoms, forming a four-membered 1,3,2-dioxaborolane ring.
Fluorine-substituted phenyl group
A phenyl group (a six-membered aromatic ring) with a fluorine atom at the 3-position and a methyl group at the 5-position.
Four methyl groups
Attached to the carbon atoms adjacent to the boron atom.
Uses
Organic synthesis and medicinal chemistry The compound is commonly used as a reagent in various organic reactions, such as cross-coupling reactions and Suzuki-Miyaura coupling.
Stability and compatibility
The compound is known for its stability and compatibility with various reaction conditions, making it a valuable reagent for a wide range of organic transformations.
Applications
Synthesis of pharmaceuticals, agrochemicals, and materials science Due to its unique structure and reactivity, the compound is a valuable tool in the synthesis of various products in different fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1583286-47-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,8,3,2,8 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1583286-47:
(9*1)+(8*5)+(7*8)+(6*3)+(5*2)+(4*8)+(3*6)+(2*4)+(1*7)=198
198 % 10 = 8
So 1583286-47-8 is a valid CAS Registry Number.
1583286-47-8Relevant articles and documents
Radical Metal-Free Borylation of Aryl Iodides
Pinet, Sandra,Liautard, Virginie,Debiais, Mégane,Pucheault, Mathieu
, p. 4759 - 4768 (2017)
A simple metal-free borylation of aryl iodides mediated by a fluoride sp 2 -sp 3 diboron adduct is described. The reaction conditions are compatible with various functional groups. Electronic effects of substituents do not affect the borylation while steric hindrance does. The reaction proceeds via a radical mechanism in which pyridine serves to stabilize the boryl radicals, generated in situ.
Rhodium-catalyzed intermolecular C-H silylation of arenes with high steric regiocontrol
Chen, Cheng,Hartwig, John F.
, p. 853 - 857 (2014/03/21)
Regioselective C-H functionalization of arenes has widespread applications in synthetic chemistry. The regioselectivity of these reactions is often controlled by directing groups or steric hindrance ortho to a potential reaction site. Here, we report a catalytic intermolecular C-H silylation of unactivated arenes that manifests very high regioselectivity through steric effects of substituents meta to a potential site of reactivity. The silyl moiety can be further functionalized under mild conditions but is also inert toward many common organic transformations, rendering the silylarene products useful building blocks. The remote steric effect that we observe results from the steric properties of both the rhodium catalyst and the silane.
