15833-80-4

Basic information

• Product Name: 3,3-dimethylbutane-1,2,4-triol
• Synonyms: 3,3-dimethylbutane-1,2,4-triol;3,3-Dimethyl-1,2,4-butanetriol;Einecs 239-936-1
• CAS NO: 15833-80-4
• Molecular Formula: C₆H₁₄O₃
• Molecular Weight: 134.17356
• EINECS: 239-936-1
• Mol File: 15833-80-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 72 °C
• Boiling Point: 286.2°Cat760mmHg
• Flash Point: 141.8°C
• Appearance: /
• Density: 1.113g/cm³
• Vapor Pressure: 0.000304mmHg at 25°C
• Refractive Index: 1.482
• PKA: 14.13±0.20(Predicted)
• CAS DataBase Reference: 3,3-dimethylbutane-1,2,4-triol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-dimethylbutane-1,2,4-triol(15833-80-4)
• EPA Substance Registry System: 3,3-dimethylbutane-1,2,4-triol(15833-80-4)

Safety Data

• Hazardous Substances Data: 15833-80-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H14O3/c1-6(2,4-8)5(9)3-7/h5,7-9H,3-4H2,1-2H3

Upstream product

• 79-50-5 pantolactone 
• 5447-64-3 diethyl 3,3-dimethyl-2-ketosuccinate 
• 371198-97-9 3,3-dimethyl-2-(2-tetrahydrofuryloxy)-1,4-butanediol 
• 371198-80-0 3,3-dimethyl-2-(2-tetrahydrofuryloxy)-4-butanolide 

Downstream Products

• 1329997-09-2 (Z)-1,4-dibenzyloxy-3,3-dimethyl-2-(trimethylsilyloxy)-1-butene 
• 1329997-13-8 (4R,5R,9R,10R)-1,4-bis(benzyloxy)-11-(tert-butyldimethylsilyloxy)-9,10-(2,2-dimethyl-1,3-dioxolane)-7-(1,3-dithiane)-5-hydroxy-2,2-dimethylundecan-3-one 
• 1329997-14-9 (4R,5R,9R,10R)-1,4-bis(benzyloxy)-11-(tert-butyldimethylsilyloxy)-9,10-(2,2-dimethyl-1,3-dioxolane)-5-methoxy-2,2-dimethylundecan-3,7-dione 
• 1329997-15-0 (4R,5R,9R,10R)-1,4-bis(benzyloxy)-11-(tert-butyldimethylsilyloxy)-9,10-(2,2-dimethyl-1,3-dioxolane)-5-hydroxy-2,2-dimethylundecan-3,7-dione 

Relevant articles and documents

Geminal dimethyl-substituted functionalized C4-synthons from pantolactone

Some geminal dimethyl-substituted functionalized C4-synthons were prepared on the basis of (±)-pantolactone.

CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF

Disclosed herein are novel cytotoxic peptides of formula (I) as described herein: Formula (I) and the use of such peptides in making immunoconjugates (i.e Antibody Drug Conjugates) Also described herein are immunoconjugates (i.e Antibody Drug Conjugates) comprising such novel cytotoxic peptide linked to an antigen binding moiety, such as an antibody; where such immunoconjugates are useful for treating cell proliferative disorders. The invention further provides pharmaceutical compositions comprising these immunoconjugates, compositions comprising the immunoconjugates with a therapeutic co-agent, and methods to use these immunoconjugates and compositions for treating cell proliferation disorders.