158331-18-1

Basic information

• Product Name: 3-BROMO-6,7-DIHYDRO-5H-[1]PYRINDINE
• Synonyms: 3-BROMO-6,7-DIHYDRO-5H-[1]PYRINDINE;3-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridine;3-BROMO-6,7-DIHYDRO-5H-[1]PYRIDINE
• CAS NO: 158331-18-1
• Molecular Formula: C8H8BrN
• Molecular Weight: 198.05982
• Mol File: 158331-18-1.mol
• Article Data: 12

Chemical Properties

• Melting Point: 65-67 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 236.409°C at 760 mmHg
• Flash Point: 96.777°C
• Appearance: /
• Density: 1.548g/cm³
• Vapor Pressure: 0.073mmHg at 25°C
• Refractive Index: 1.608
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 3.83±0.20(Predicted)
• CAS DataBase Reference: 3-BROMO-6,7-DIHYDRO-5H-[1]PYRINDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-6,7-DIHYDRO-5H-[1]PYRINDINE(158331-18-1)
• EPA Substance Registry System: 3-BROMO-6,7-DIHYDRO-5H-[1]PYRINDINE(158331-18-1)

Safety Data

• Hazardous Substances Data: 158331-18-1(Hazardous Substances Data)

Usage

General Description

3-Bromo-6,7-dihydro-5H-[1]pyrindine is a chemical compound with the molecular formula C8H8BrN. As such, it contains eight atoms of carbon (C), eight atoms of hydrogen (H), one atom of bromine (Br), and one atom of nitrogen (N). 3-BROMO-6,7-DIHYDRO-5H-[1]PYRINDINE belongs to the family of pyridines, which are aromatic compounds that contain a six-membered ring with five carbon atoms and one nitrogen atom. It also has a bromine atom attached, which results in bromination - a chemical reaction that involves the addition of bromine. Its detailed chemical properties, including reactivity, toxicity, and potential uses, are not widely documented in the accessible literature. Currently, it is mainly used for research and development purposes.

InChI:InChI=1/C8H8BrN/c9-7-4-6-2-1-3-8(6)10-5-7/h4-5H,1-3H2

Upstream product

• 533-37-9 2,3-cyclopentenopyridine 
• 7148-07-4 1-pyrrolidinocyclopent-1-ene 
• 114078-88-5 5-bromo-1,2,3-triazine 
• 88499-85-8 6,7-dihydro-5H-cyclopenta[b]pyridin-2-ol 

Downstream Products

• 1336955-89-5 3-bromo-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one 
• 1379342-51-4 3-bromo-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol 

Relevant articles and documents

HISTONE ACETYLTRANSFERASE (HAT) INHIBITOR AND USE THEREOF

The present invention relates to a histone acetyltransferase (HAT) inhibitor. Provided are a compound represented by general formula I, a pharmaceutically acceptable salt, a stereoisomer, an enantiomer, a diastereomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the treatment of various HAT-related diseases or conditions.

6,5-FUSED HETEROARYL PIPERIDINE ETHER ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR

The present invention is directed to 6,5-fused heteroarylpiperidine ether compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Cyclic gyrase and topoisomerase IV inhibitor

The invention belongs to the technical field of medicament, and particularly relates to a compound shown in formula (I) (please see the formula (I) in the description), and acceptable salt, ester or stereoisomer of the compound in pharmacy. R1, R2, a ring