158392-26-8

Basic information

• Product Name: N-(3-bromopropyl)-p-nitrobenzamide
• Synonyms: N-(3-bromopropyl)-p-nitrobenzamide
• CAS NO: 158392-26-8
• Molecular Weight: 287.113
• Mol File: 158392-26-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3-bromopropyl)-p-nitrobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-bromopropyl)-p-nitrobenzamide(158392-26-8)
• EPA Substance Registry System: N-(3-bromopropyl)-p-nitrobenzamide(158392-26-8)

Safety Data

• Hazardous Substances Data: 158392-26-8(Hazardous Substances Data)

Upstream product

• 5003-71-4 3-bromopropylamine hydrochloride 
• 122-04-3 4-nitro-benzoyl chloride 
• 62-23-7 4-nitro-benzoic acid 
• 18370-81-5 (3-bromopropyl)amine 

Downstream Products

• 1261481-21-3 2-(p-nitrophenyl)-5,6-dihydro-4H-1,3-oxazine hydrobromide 
• 1246248-25-8 tert-Butyl {3-[(4-aminobenzoyl)amino]propyl}methylcarbamate 
• 134221-66-2 1-Methyl-2-(4-nitro-phenyl)-3-phenyl-3,4,5,6-tetrahydro-pyrimidin-1-ium; iodide 
• 134221-75-3 N-(3-Methylamino-propyl)-4-nitro-N-phenyl-benzamide 
• 134221-86-6 2-(p-nitrophenyl)-1-phenyl-1,4,5,6-tetrahydropyrimidine 
• 21977-88-8 2-(4-nitrophenyl)-5,6-dihydro-4H-1,3-thiazine 
• 39885-38-6 2-(4-nitrophenyl)-5,6-dihydro-4H-[1,3]-oxazine 
• 134221-61-7 4-Nitro-N-(3-phenylamino-propyl)-benzamide 

Relevant articles and documents

AMIDE DERIVATIVE

The present invention relates to a compound or a pharmacologically acceptable salt thereof that has an excellent antagonistic effect on a neurokinin NK1 receptor, a neurokinin NK2 receptor, and a muscarine M3 receptor and is useful as a therapeutic agent for bronchial asthma, chronic obstructive pulmonary disease, or the like. A compound represented by general formula (I): [wherein R1 represents a hydrogen atom, a C1-C6 alkyl group, or the like; R2 represents a hydrogen atom, a C1-C6 alkyl group, or the like; R3 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group A, or the like; R4 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group A, or the like; L1 represents a C1-C10 alkylene group or the like; L2 represents a carbonyl group, a group represneted by the formula -N(R5)-C(=O)-, a group represented by the formula -C(=O)-N(R5)-, or the like; R5 represents a hydrogen atom, a C1-C6 alkyl group, or the like; E represents a phenylene group that may be substituted with 1 to 4 group(s) independently selected from Substituent Group A, or the like; m is an integer of 1 to 4; n is an integer of 0 to 4; p is an integer of 0 to 2; q is an integer of 1 to 10; r is 1 or 2; s is 0 or 1; and Substituent Group A represents the group consisting of a halogen atom, a C1-C6 alkyl group, C1-C6 halogenated alkyl group, or the like] or a pharmacologically acceptable salt thereof.