158664-74-5

Basic information

• Product Name: 3-hydroxy-3-(3'-methoxy-4'-methylphenyl)propionic acid
• CAS NO: 158664-74-5
• Molecular Weight: 210.23
• Mol File: 158664-74-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-3-(3'-methoxy-4'-methylphenyl)propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-3-(3'-methoxy-4'-methylphenyl)propionic acid(158664-74-5)
• EPA Substance Registry System: 3-hydroxy-3-(3'-methoxy-4'-methylphenyl)propionic acid(158664-74-5)

Safety Data

• Hazardous Substances Data: 158664-74-5(Hazardous Substances Data)

Upstream product

• 24973-22-6 3-methoxy-4-methylbenzaldehyde 
• 64-19-7 acetic acid 

Relevant articles and documents

Indenone synthesis. Improved synthetic protocol and effect of substitution on the intramolecular Friedel-Crafts acylation

An improved protocol for the construction of substituted indenones is presented. Also the effect of substitution on the intramolecular Friedel-Crafts acylation was noted. Specifically, if there is no substitution at the 2-position of the indenone poor yields of cyclized material were obtained, if at all, while the substitution of a methyl or ethyl group greatly improved the yield of cyclized material. Placement of a large group (e. g., benzyl) resulted in a diminuation of the improved yield. The new synthetic procedure could, in principle, allow for the construction of 2,3-disubstituted indenones. One example of this reaction mode was presented.