15870-69-6

Basic information

• Product Name: 2-[4-(bromomethyl)phenyl]-1H-isoindole-1,3(2H)-dione
• Synonyms: 2-[4-(Bromomethyl)phenyl]isoindole-1,3-dione
• CAS NO: 15870-69-6
• Molecular Formula: C₁₅H₁₀BrNO₂
• Molecular Weight: 316.1494
• Mol File: 15870-69-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 472.3°C at 760 mmHg
• Flash Point: 239.4°C
• Density: 1.61g/cm³
• Vapor Pressure: 4.34E-09mmHg at 25°C
• Refractive Index: 1.686
• CAS DataBase Reference: 2-[4-(bromomethyl)phenyl]-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(bromomethyl)phenyl]-1H-isoindole-1,3(2H)-dione(15870-69-6)
• EPA Substance Registry System: 2-[4-(bromomethyl)phenyl]-1H-isoindole-1,3(2H)-dione(15870-69-6)

Safety Data

• Hazardous Substances Data: 15870-69-6(Hazardous Substances Data)

Usage

General Description

2-[4-(bromomethyl)phenyl]-1H-isoindole-1,3(2H)-dione is a chemical compound with a structure consisting of an isoindole ring, a bromomethylphenyl group, and a carbonyl group. It is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its potential pharmacological and biological activities. 2-[4-(bromomethyl)phenyl]-1H-isoindole-1,3(2H)-dione has also been studied for its potential use in materials science and as a reagent in organic chemistry. Its unique structure and reactivity make it a versatile building block for the synthesis of various organic compounds, and it is an important intermediate in the production of a wide range of chemicals. However, it should be handled with caution due to its potential hazards, and proper safety precautions should be followed when working with this compound.

Upstream product

• 2142-03-2 2-p-tolylisoindoline-1,3-dione 
• 85-44-9 phthalic anhydride 
• 106-49-0 p-toluidine 

Downstream Products

• 165605-29-8 4-<(4-N-phthalamidophenyl)methyl>-1-<2-(4-nitrophenyl)ethyl>imidazolidine-2,5-dione 
• 138476-44-5 4-(N-phthalimidyl)benzylphosphonic acid 
• 913267-39-7 2-{4-[3-(4-tert-butyl-benzyl)-2-oxo-imidazolidin-1-ylmethyl]phenyl}-isoindole-1,3-dione 

Relevant articles and documents

Microwave-assisted benzyl mono- and dibromination in diethyl carbonate as environmentally friendly alternative to radical bromination in carbon tetrachloride

An environmentally friendly benzyl mono- and di-bromination synthetic procedure was developed that is superior to the classic carbon tetrachloride bromination procedure in both reaction time and isolated yield. This new reaction was performed in diethyl carbonate as reaction media using microwave instead of conventional heating. Both the solvent and the brominating reagent N-bromosuccinimide (prepared from succinimide obtained from the reaction mixture) are recyclable. Practically, the preparation of our target compounds was completed in less than two hours. The Royal Society of Chemistry.

SUBSTITUTED CYCLIC UREA DERIVATIVES AND THE USE THEREOF AS VANILLOID RECEPTOR 1 MODULATORS

The invention relates to substituted cyclic urea derivatives, wherein X represents O, S or N-C=N; m is 1 or 2; n is 1 or 2; p1 and p2 represent independently 0, 1, 2 or 3, and the sum of p1 and p2 is 0, 1, 2 or 3. The invention also relates to methods for producing said derivatives, to drugs containing these compounds and to the use of these compounds for producing drugs. The inventive drugs are especially useful for vanilloid receptor 1 (VR1/TRPV1) regulation, preferably for vanilloid receptor 1 (VR1/TRPV1) inhibition and/or vanilloid receptor 1 (VR1/TRPV1) stimulation.