158719-53-0

Basic information

• Product Name: methyl (4S,5S,1'S)-5-<1'-(benzyloxy)ethyl>-2-(p-methoxyphenyl)-2-oxazoline-4-carboxylate
• Synonyms: methyl (4S,5S,1'S)-5-<1'-(benzyloxy)ethyl>-2-(p-methoxyphenyl)-2-oxazoline-4-carboxylate
• CAS NO: 158719-53-0
• Molecular Weight: 369.417
• Mol File: 158719-53-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (4S,5S,1'S)-5-<1'-(benzyloxy)ethyl>-2-(p-methoxyphenyl)-2-oxazoline-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (4S,5S,1'S)-5-<1'-(benzyloxy)ethyl>-2-(p-methoxyphenyl)-2-oxazoline-4-carboxylate(158719-53-0)
• EPA Substance Registry System: methyl (4S,5S,1'S)-5-<1'-(benzyloxy)ethyl>-2-(p-methoxyphenyl)-2-oxazoline-4-carboxylate(158719-53-0)

Safety Data

• Hazardous Substances Data: 158719-53-0(Hazardous Substances Data)

Upstream product

• 81445-44-5 (S)-2-(benzyloxy)propanal 
• 67567-57-1 2-(p-methoxyphenyl)-5-methoxyoxazole 
• 158719-52-9 cis-(4R,5S,1'S)-5-<1'-(benzyloxy)ethyl>-4-(methoxycarbonyl)-2-(p-methoxyphenyl)-2-oxazoline 

Relevant articles and documents

Highly Diastereoselective Synthesis of 2-Oxazoline-4-carboxylates by Formal Cycloadditions of a 5-Alkoxyoxazole with α-Alkoxy Aldehydes Catalyzed by Tin(IV) Chloride

The formal cycloaddition of 5-methoxy-2-(p-methoxyphenyl)oxazole with 2(S)-(benzyloxy)propanal and 2(S)-propanal in the presence of tin(IV) chloride gave cis-(4R,5S,1'S)- and trans-(4S,5S,1'S)-5-(1'-alkoxyethyl)-4-(methoxycarbonyl)-2-(p-methoxyphenyl)-2-oxazolines with high diastereoselectivity (94 and 92percent selectivity, respectively).A similar reaction of 5-methoxy-2-(p-methoxyphenyl)oxazole with 2,3-di-O-benzyl-D-glyceraldehyde gave methyl cis-(4S,5R,1'R)-2-(p-methoxyphenyl)-5--2-oxazoline-4-carboxylate with high diastereoselectivity (>95percent selectivity), and the latter was easily converted to biologically important chiral 2-amino-1,3,4,5-tetrol derivatives.