1588429-76-8

Basic information

• Product Name: 5-bromo-1, 3-dimethyl-3-((phenylsulfonyl)methyl)indolin-2-one
• Synonyms: 5-bromo-1, 3-dimethyl-3-((phenylsulfonyl)methyl)indolin-2-one
• CAS NO: 1588429-76-8
• Molecular Weight: 394.289
• Mol File: 1588429-76-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-bromo-1, 3-dimethyl-3-((phenylsulfonyl)methyl)indolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-1, 3-dimethyl-3-((phenylsulfonyl)methyl)indolin-2-one(1588429-76-8)
• EPA Substance Registry System: 5-bromo-1, 3-dimethyl-3-((phenylsulfonyl)methyl)indolin-2-one(1588429-76-8)

Safety Data

• Hazardous Substances Data: 1588429-76-8(Hazardous Substances Data)

Upstream product

• 1353568-76-9 N-methyl-N-(4-bromophenyl)methacrylamide 
• 66003-76-7 Diphenyliodonium triflate 
• 882-33-7 diphenyldisulfane 
• 80-17-1 benzenesufonyl hydrazide 
• 106-40-1 4-bromo-aniline 
• 618-41-7 Benzenesulfinic acid 
• 7600-35-3 N-(4-bromophenyl)methacrylamide 

Relevant articles and documents

Visible-Light-Induced 3-Component Synthesis of Sulfonylated Oxindoles by Fixation of Sulfur Dioxide

A novel, visible-light-induced 3-component synthesis of sulfonylated oxindoles from N-arylacrylamides, diaryliodonium salts and sulfur dioxide is described. The reaction provides simple access to a wide variety of 3-[(arylsulfonyl)methyl]indolin-2-ones in moderate to excellent yields under mild conditions at room temperature. The transformation proceeds in the absence of any external photosensitizer and enables an efficient, solely visible-light-driven fixation of sulfur dioxide.

Transition-Metal-Free TBAI-Facilitated Addition-Cyclization of N-Methyl-N-arylacrylamides with Arylaldehydes or Benzenesulfonohydrazides: Access to Carbonyl- and Sulfone-Containing N-Methyloxindoles

A highly efficient addition-cyclization of N-methyl-N-arylacrylamides with arylaldehydes or benzenesulfonohydrazides was developed using a catalytic amount of the quaternary ammonium salt (TBAI) under metal-free conditions, leading to the carbonyl- and sulfone-containing oxindoles. Compared to previous methods, which require excessive amounts of explosive organic peroxides and precious or toxic metal reagents, the present protocol, which gave access to 3,3-disubstituted oxindoles, is a safe and green approach, resulting in the formation of various useful carbonyl- and sulfone-containing oxindoles in yields of 40-94%.

Catalyst-free direct arylsulfonylation of N-arylacrylamides with sulfinic acids: A convenient and efficient route to sulfonated oxindoles

A simple, efficient and catalyst-free procedure has been developed for the construction of sulfonated oxindoles via the direct arylsulfonylation of N-arylacrylamides with sulfinic acids. The present protocol, which simply utilizes cheap oxidants, readily-available starting materials, and catalyst-free conditions, provides an alternative and highly attractive approach to a series of sulfonated oxindoles with high atom efficiency and excellent functional group tolerance. This journal is the Partner Organisations 2014.