158951-61-2

Basic information

• Product Name: benzyl (S)-N-[2-(1H-indol-3-yl)-1-phenylcarbamoylethyl]carbamate
• Synonyms: benzyl (S)-N-[2-(1H-indol-3-yl)-1-phenylcarbamoylethyl]carbamate
• CAS NO: 158951-61-2
• Molecular Weight: 413.476
• Mol File: 158951-61-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl (S)-N-[2-(1H-indol-3-yl)-1-phenylcarbamoylethyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (S)-N-[2-(1H-indol-3-yl)-1-phenylcarbamoylethyl]carbamate(158951-61-2)
• EPA Substance Registry System: benzyl (S)-N-[2-(1H-indol-3-yl)-1-phenylcarbamoylethyl]carbamate(158951-61-2)

Safety Data

• Hazardous Substances Data: 158951-61-2(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 7432-21-5 N-carbobenzyloxy-L-tryptophane 
• 64693-64-7 N^α-benzyloxycarbonyl-L-tryptophyl chloride 
• 13058-16-7 N-[(phenylmethoxy)carbonyl]-DL-tryptophan 

Downstream Products

• 127592-76-1 (S)-2-amino-3-(1H-indole-3-yl)-N-phenylpropionamide 
• 911675-43-9 N-Boc-Tyr(Bn)-Lys(Boc)-Trp-NHPh 

Relevant articles and documents

Organocatalysis of asymmetric aldol reaction in water: Comparison of catalytic properties of (S)-valine and (S)-proline amides

(S)-Valine amides containing (S)- or (R)-α-phenylethyl substituents at N1 atom efficiently catalyze asymmetric aldol reactions between cyclic (heterocyclic) ketones and aromatic aldehydes in water, predominantly giving rise to the aldol anti-di

COMPOUNDS USEFUL AS MODULATORS OF THE PROTEASOME ACTIVITY

The present invention relates to the use of compounds of the following general formula (I): wherein no is 0 or 1, and when no is 1, X = CH2 or X = NCH2C6H5; R1 is OH, or a OR10 group, or a group of formula NH-(CH2)n1-R11; R2 is H, or an alkyl group, or a group of formula (CH2)n2-(CO)n3-NR13R14; R3 is H, or an alkyl group; R4 is H, or Boc, or Z; R5 is H, or Boc, or Z ; R6 is a OR16 group; R7 and R8 are H, or a halogen atom, as modulators of the proteasome activity, in the frame of the preparation of a medicament useful for the prevention or treatment of diseases wherein the proteasome is involved, or the preparation of cosmetic compositions, or of phytosanitary compositions.