1589590-87-3 Usage
Description
Canagliflozin α Isomer is a pharmaceutical compound that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It is an enantiomer of Canagliflozin, which is used for the treatment of type 2 diabetes and obesity. The α Isomer exhibits specific properties that differentiate it from the other isomers, making it a unique compound with potential applications in the medical field.
Uses
Used in Pharmaceutical Industry:
Canagliflozin α Isomer is used as an active pharmaceutical ingredient for the development of medications targeting type 2 diabetes and obesity. Its role as an SGLT2 inhibitor helps regulate glucose levels in the body, providing a potential therapeutic option for patients suffering from these conditions.
Used in Research and Development:
Canagliflozin α Isomer serves as a valuable compound in the research and development of new drugs and therapies. Its unique properties allow scientists to study its interactions with biological systems and explore its potential in treating various diseases beyond diabetes and obesity.
Used in Quality Control and Impurity Profiling:
In the pharmaceutical manufacturing process, Canagliflozin α Isomer can be used as a reference material for quality control and impurity profiling. This helps ensure the safety, efficacy, and purity of the final drug product by comparing it to the known properties of the α Isomer.
Used in Drug Interaction Studies:
Canagliflozin α Isomer can be employed in drug interaction studies to understand its potential effects when combined with other medications. This information is crucial for healthcare providers and patients to make informed decisions about drug combinations and potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1589590-87-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,8,9,5,9 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1589590-87:
(9*1)+(8*5)+(7*8)+(6*9)+(5*5)+(4*9)+(3*0)+(2*8)+(1*7)=243
243 % 10 = 3
So 1589590-87-3 is a valid CAS Registry Number.
1589590-87-3Relevant articles and documents
Stereoselective Preparation of C-Aryl Glycosides via Visible-Light-Induced Nickel-Catalyzed Reductive Cross-Coupling of Glycosyl Chlorides and Aryl Bromides
Mou, Ze-Dong,Wang, Jia-Xi,Zhang, Xia,Niu, Dawen
, p. 3025 - 3029 (2021/05/27)
A nickel-catalyzed cross-coupling reaction of glycosyl chlorides with aryl bromides has been developed. The reaction proceeds smoothly under visible-light irradiation and features the use of bench-stable glycosyl chlorides, allowing the highly stereoselective synthesis of C-aryl glycosides. (Figure presented.).
Preparation method of SGLT-2 inhibitor and intermediate
-
, (2021/05/19)
The invention discloses a preparation method of an SGLT-2 inhibitor and an intermediate. The method comprises the following steps: (1) reacting a compound A with chlorosilane under the action of an acid-binding agent to generate a compound B; (2) mixing the compound B and a compound C to obtain a compound D; and (3) reacting the compound D with a reducing agent and a catalyst to obtain the SGLT-2 inhibitor compound.
Preparation method of canagliflozin
-
, (2020/02/14)
The invention discloses a preparation method of canagliflozin. According to the method, the reaction of each step in a route is improved, so that the conversion rate of raw materials is increased, andintroduction of potential toxic compounds is avoided. In addition, reaction conditions are mild; operation is simple; purity of an obtained product is high; quality of drugs is improved; and the preparation method is suitable for industrial production.
