158977-79-8Relevant articles and documents
Synthesis of pyridazine acetic acid derivatives possessing aldose reductase inhibitory activity and antioxidant properties
Coudert,Albuisson,Boire,Duroux,Bastide,Couquelet
, p. 471 - 477 (2007/10/02)
N-Acetic acid derivatives of 4-carboxy-6-arylpyridazin-3-ones were synthesized for the dual purpose of inhibiting aldose reductase and exhibiting antioxidant properties. All the prepared compounds showed a significant in vitro aldose reductase inhibitory