15898-46-1

Basic information

• Product Name: sodium 3-nitrobenzenesulfinate
• Synonyms: sodium 3-nitrobenzenesulfinate
• CAS NO: 15898-46-1
• Molecular Weight: 209.158
• Mol File: 15898-46-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: sodium 3-nitrobenzenesulfinate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium 3-nitrobenzenesulfinate(15898-46-1)
• EPA Substance Registry System: sodium 3-nitrobenzenesulfinate(15898-46-1)

Safety Data

• Hazardous Substances Data: 15898-46-1(Hazardous Substances Data)

Upstream product

• 121-51-7 3-nitrobenzenesulphonyl chloride 

Downstream Products

• 30556-82-2 methyl 3-nitrobenzene-1-sulfinate 
• 41687-30-3 3-(β-hydroxyethylsulfonyl)nitrobenzene 
• 370-47-8 (3-nitrophenyl)(trifluoromethyl)sulfane 
• 41024-49-1 2-((3-nitrophenyl)sulfonyl)-1-phenylethan-1-one 
• 34418-84-3 1-nitro-2-((3-nitrophenyl)sulfonyl)benzene 
• 79048-31-0 tributyl(3-nitrophenyl)stannane 
• 72496-79-8 3-<(3-nitrophenyl)thio>indole 
• 1627147-81-2 1,3-dimethyl-3-(((3-nitrophenyl)sulfonyl)methyl)indolin-2-one 
• 2113-58-8 3-nitro-1,1'-biphenyl 
• 1548-72-7 1-nitro-3-(trifluoromethylsulfonyl)benzene 
• 31803-44-8 5-(3-amino-benzenesulfonyl)-3-methyl-isothiazol-4-ylamine 
• 3729-50-8 4-[1-methyl-2-(3-nitro-benzenesulfonyl)-ethyl]-morpholine 
• 143878-51-7 1-(3,3-Dimethyl-but-1-yne-1-sulfonyl)-3-nitro-benzene 
• 143878-50-6 1-Nitro-3-(2-phenyl-ethynesulfonyl)-benzene 

Relevant articles and documents

Preparation method of M-nitro - β β-hydroxyethyl sulfone (by machine translation)

The invention discloses a method for preparing M-nitro - β β-hydroxyethyl sulfone, belongs to the technical field of dye chemical intermediate manufacturing, and comprises the following steps: (1) adding an aqueous hydrazine hydrate solution, slowly or repeatedly adding m-nitrobenzenesulfonyl chloride; 40~70 °C) dropwise adding ethylene oxide, controlling 50~70 °C the temperature 0.5~1.5, and 2 using pH7.0~7.6 dilute sulfuric acid to maintain pH5.0~7.0, filtering, and obtaining m-hydroxyethyl sulfone. (Z - β β-hydroxyethyl sulfone). Compared with a traditional process for improving the high-salinity wastewater and the nunitz ? waste residue, the process is cleaner, environment-friendly; the process is simple, the required equipment is few, and the investment of equipment is greatly reduced; and the equipment investment can be greatly reduced. 20% 5 tonnes 98.5% 70 kg (by machine translation)

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The present invention features a compound of formula I: or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.

Synthesis of oxindoles through silver-catalyzed trifluoromethylation-, difluoromethylation- and arylsulfonylation-cyclization reaction of N-arylacrylamides

Efficient synthesis of trifluoromethyl and difluoromethyl-substituted oxindoles was achieved by reacting Langlois reagent or Baran reagent with N-arylacrylamides. However, the reaction of aryl sulfinic acid sodium salts with N-arylacrylamides did not give the desulfinative products, instead, aryl sulfonated products were produced. Copyright