15930-57-1

Basic information

• Product Name: Benzamide, N,N-diethyl-3,5-dimethyl-
• CAS NO: 15930-57-1
• Molecular Formula: C13H19NO
• Molecular Weight: 205.3
• Mol File: 15930-57-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N-diethyl-3,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N-diethyl-3,5-dimethyl-(15930-57-1)
• EPA Substance Registry System: Benzamide, N,N-diethyl-3,5-dimethyl-(15930-57-1)

Safety Data

• Hazardous Substances Data: 15930-57-1(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 556-97-8 1-chloro-3,5-dimethylbenzene 
• 109-89-7 diethylamine 
• 499-06-9 3,5-dimethylbenzoic acid 

Downstream Products

• 1416990-29-8 C₁₄H₁₉NO₂ 
• 1527479-97-5 N,N-diethyl-2-iodo-3,5-dimethylbenzamide 
• 1416990-31-2 C₁₅H₂₃NO₄S 
• 1416990-30-1 C₁₄H₂₁NO₂ 

Relevant articles and documents

PREPARATION OF AROMATIC CARBOXYAMIDES BY A PALLADIUM-CATALYZED CARBONYLATION REACTION

The present invention relates to a process for the preparation of aromatic carboxyamides of formula I, which can be obtained by a palladium-catalyzed carbonylation reaction of aromatic chlorides of formula II, amines of formula III and carbon monoxide in the presence of 1,5,7-triazabi-cyclo[4.4.0]dec-5-ene. The invention further relates to a process for the preparation of aryl-5-trifluoromethyl-1,2,4-oxadiazoles, which are known for controlling phytopathogenic fungi.

Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity

A series of analogs of the immunomodulary drugs lenalidomide (1) and pomalidomide (2), in which the amino group is replaced with various isosteres, was prepared and assayed for immunomodulatory activity and activity against cancer cell lines. The 4-methyl and 4-chloro analogs 4 and 15, respectively, displayed potent inhibition of tumor necrosis factor-α (TNF-α) in LPS-stimulated hPBMC, potent stimulation of IL-2 in a human T cell co-stimulation assay, and anti-proliferative activity against the Namalwa lymphoma cell line. Both of these analogs displayed oral bioavailability in rat.