159392-24-2Relevant articles and documents
Cyclosporin A: Regioselective Ring Opening and Fragmentation Reactions via Thioamides. A Route to Semisynthetic Cyclosporins
Eberle, Marcel K.,Jutzi-Eme, Anne-Marie,Nuninger, Francois
, p. 7249 - 7258 (1994)
Cyclosporin A (1a) served as the starting material for the semisynthetic preparation of a variety of novel cyclosporins.Acetylcyclosporin A (2) was treated with Lawesson's reagent.From the reaction mixture, three novel acetylated thioamides were isolated: