159639-71-1

Basic information

• Product Name: N²,N⁶-dibenzoyl-2-aminoadenosine
• CAS NO: 159639-71-1
• Molecular Weight: 490.475
• Mol File: 159639-71-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N²,N⁶-dibenzoyl-2-aminoadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: N²,N⁶-dibenzoyl-2-aminoadenosine(159639-71-1)
• EPA Substance Registry System: N²,N⁶-dibenzoyl-2-aminoadenosine(159639-71-1)

Safety Data

• Hazardous Substances Data: 159639-71-1(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 2096-10-8 adenosine-2-amine 

Relevant articles and documents

Interaction of (2'-5') and (3'-5') linked 2-aminoadenylyl-2- aminoadenosines with polyuridylic acid

2'-5' and 3'-5' linked 2-aminoadenylyl-2-aminoadenosines [(2'5')n2Apn2A (1) and (3'-5')n2Apn2A (2)] were synthesized by condensation of 5'-O- monomethoxytrityl-N2,N6-dibenzoyl-2-aminoadenosine and N2,N6,2',3'-O- tetrabenzoyl-2-aminoadenosine 5'-phosphate using dicyclohexylcarbodiimide (DCC). The conformational properties of these dimers 1 and 2 were examined by UV, NMR and CD spectroscopy. The results reveal that the 2'-5'-isomer 1 takes a stacked conformation, which contains a larger base-base overlap and is room stable against thermal perturbation with respect to the 3'-5'-isomer 2. Interactions of 1 and 2 with polyuridylic acid (Poly (U)) were also examined by Tm, mixing curves, UV and CD spectra. Both the dinucleoside isomers 1 and 2 formed a complex of 1 : 2 stoichiometry with poly(U), which was much more stable than that of the corresponding ApA isomer