1597448-33-3

Basic information

• Product Name: C₂₀H₁₅NO₃
• Synonyms: C₂₀H₁₅NO₃
• CAS NO: 1597448-33-3
• Molecular Weight: 317.344
• Mol File: 1597448-33-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₅NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₅NO₃(1597448-33-3)
• EPA Substance Registry System: C₂₀H₁₅NO₃(1597448-33-3)

Safety Data

• Hazardous Substances Data: 1597448-33-3(Hazardous Substances Data)

Upstream product

• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 106-40-1 4-bromo-aniline 
• 1597448-32-2 C₂₁H₁₇NO₃ 
• 5730-76-7 methyl 4’-amino-[1,1’-biphenyl]-4-carboxylate 

Downstream Products

• 1597448-34-4 C₂₆H₂₀N₂O₂ 

Relevant articles and documents

Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors

A series of bis-aromatic amides was designed, synthesized, and evaluated as a new class of inhibitors with IC50 values in the micromolar range against protein tyrosine phosphatase 1B (PTP1B). Among them, compound 15 displayed an IC50 value of 2.34 ± 0.08 μM with 5-fold preference over TCPTP. More importantly, the treatment of CHO/HIR cells with compound 15 resulted in increased phosphorylation of insulin receptor (IR), which suggested extensive cellular activity of compound 15. These results provided novel lead compounds for the design of inhibitors of PTP1B as well as other PTPs.