159858-00-1

Basic information

• Product Name: alloc-D-Phe-Phe-Su
• CAS NO: 159858-00-1
• Molecular Weight: 493.516
• Mol File: 159858-00-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: alloc-D-Phe-Phe-Su(CAS DataBase Reference)
• NIST Chemistry Reference: alloc-D-Phe-Phe-Su(159858-00-1)
• EPA Substance Registry System: alloc-D-Phe-Phe-Su(159858-00-1)

Safety Data

• Hazardous Substances Data: 159858-00-1(Hazardous Substances Data)

Upstream product

• 159857-98-4 alloc-D-Phe-OSu 
• 152507-71-6 (R)-(N-allyloxycarbonyl)phenylalanine 
• 673-06-3 D-(R)-phenylalanine 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 159857-99-5 alloc-D-Phe-Phe 

Downstream Products

• 159858-03-4 Carbonic acid 4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyl ester 4-nitro-phenyl ester 
• 159858-02-3 [(S)-5-[(S)-2-((R)-2-Allyloxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-5-(4-hydroxymethyl-phenylcarbamoyl)-pentyl]-carbamic acid allyl ester 
• 159858-01-2 (S)-6-Allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-hexanoic acid 

Relevant articles and documents

Cathepsin B-sensitive dipeptide prodrugs. 1. A model study of structural requirements for efficient release of doxorubicin

A series of lysosomal protease-sensitive peptides attached to doxorubicin (DOX) was prepared as model substrates for internalizing anticancer immunoconjugates and potential antimetastasis prodrugs. Rates of cathepsin B-mediated release of free drug was measured for each, and human plasma stabilities for representative examples.