1599461-74-1

Basic information

• Product Name: (Z)-ethyl 3-(allylamino)-2-benzyl-3-phenylacrylate
• Synonyms: (Z)-ethyl 3-(allylamino)-2-benzyl-3-phenylacrylate
• CAS NO: 1599461-74-1
• Molecular Weight: 321.419
• Mol File: 1599461-74-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-ethyl 3-(allylamino)-2-benzyl-3-phenylacrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-ethyl 3-(allylamino)-2-benzyl-3-phenylacrylate(1599461-74-1)
• EPA Substance Registry System: (Z)-ethyl 3-(allylamino)-2-benzyl-3-phenylacrylate(1599461-74-1)

Safety Data

• Hazardous Substances Data: 1599461-74-1(Hazardous Substances Data)

Upstream product

• 34375-90-1 but-3-en-2-amine 
• 56409-75-7 ethyl 2-benzyl-3-oxo-3-phenylpropanoate 

Relevant articles and documents

Copper-mediated oxidative transformation of N-allyl enamine carboxylates toward synthesis of azaheterocycles

A method for synthesis of 3-azabicyclo[3.1.0]hex-2-enes has been developed by intramolecular cyclopropanation of readily available N-allyl enamine carboxylates. Two complementary reaction conditions, CuBr-mediated aerobic and CuBr2-catalyzed-PhIO2-mediated systems effectively induced stepwise cyclopropanation via carbocupration of alkenes. Oxidative cyclopropane ring-opening of 5-substituted 3-azabicyclo[3.1.0]hex-2-enes was also developed for synthesis of highly substituted pyridines. In addition, diastereoselective reduction of 3-azabicyclo[3.1.0]hex-2-enes to 3-azabicyclo[3.1.0]hexanes was achieved using NaBH3CN in the presence of acetic acid.