1599467-47-6Relevant articles and documents
Reaction of arylidenehydrazono-4-aryl-2,3-dihydrothiazole-5-carbonitriles with diethyl acetylenedicarboxylate. Synthesis of (Z)-ethyl 2-[((Z)-2-(E)- arylidenehydrazono)-4-oxo-thiazolidine-5-ylidene]acetates. NMR investigation
Aly, Ashraf A.,Ishak, Esam A.,Brown, Alan B.
, p. 382 - 393 (2014/06/10)
(Z)-Ethyl 2-[((Z)-2-(E)-arylidenehydrazono)-4-oxo-thiazolidine-5-ylidene] acetates were synthesized by three different methods: (a) reaction of arylidenehydrazono-4-aryl-2,3-dihydrothiazole-5-carbonitriles with diethyl acetylenedicarboxylate (DEAD) in acetic acid with prolonged reflux, (b) reaction between thiosemicarbazones, 2-arylidenemalononitriles and DEAD under conventional conditions or microwave irradiation, (c) one-pot three-component reaction of thiosemicarbazone derivatives, ylidene and DEAD. The thiazolinone adducts were obtained in good to excellent yields. NMR of the obtained products was investigated.