15999-95-8

Basic information

• Product Name: Benzenecarboximidoyl chloride, N-(4-methylphenyl)-
• CAS NO: 15999-95-8
• Molecular Formula: C14H12ClN
• Molecular Weight: 229.709
• Mol File: 15999-95-8.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzenecarboximidoyl chloride, N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarboximidoyl chloride, N-(4-methylphenyl)-(15999-95-8)
• EPA Substance Registry System: Benzenecarboximidoyl chloride, N-(4-methylphenyl)-(15999-95-8)

Safety Data

• Hazardous Substances Data: 15999-95-8(Hazardous Substances Data)

Upstream product

• 582-78-5 N-(4-methylphenyl)benzamide 
• 116546-08-8 N-Benzylidene-p-toluidine 
• 98-88-4 benzoyl chloride 
• 106-49-0 p-toluidine 

Downstream Products

• 425366-04-7 N-p-tolyl-benzimidic acid 4-cyano-phenyl ester 
• 1095281-89-2 CH₃C(C₆H₅)N((CH₃)C₆H₄)C₃H₃N₂⁽¹⁺⁾*Cl^(1-)=CH₃C(C₆H₅)N((CH₃)C₆H₄)C₃H₃N₂Cl 
• 1428265-17-1 5,12-diphenylisoquinolino[3,4-b]phenanthridine 
• 59387-46-1 N-hydroxy-N-phenyl-N'-p-tolyl-benzamidine; hydrochloride 
• 13228-36-9 5-methyl-2-phenyl-1H-indole 
• 121910-79-0 4-isopropyl-6-methyl-2-phenylquinazoline 
• 19226-18-7 6-methyl-2-phenyl-4-(p-tolyl)quinazoline 
• 324065-73-8 N-benzyl-N′-(p-tolyl)benzimidamide 

Relevant articles and documents

Synthesis of Imidoyl Chlorides Using Phosphorus Trichloride

Abstract: The reaction of carboxamides with phosphorus trichloride under heating at 75–80°C for 1 h in the presence of a 4-dimethylaminopyridine catalyst was used to synthesize imidoyl chlorides in yields of 63–99%.

Silver-Catalyzed Cascade Cyclization Reaction of Isocyanides with Sulfoxonium Ylides: Synthesis of 3-Aminofurans and 4-Aminoquinolines

A silver-catalyzed cascade cyclization reaction of isocyanides with sulfoxonium ylides has been developed for the first time. This reaction provides a new and efficient method for the construction of highly functionalized 3-aminofurans and 4-aminoquinolines from readily available starting materials in a single step.

The impact of cation structure upon the acidity of triazolium salts in dimethyl sulfoxide

A series of triazolium salts, selected for their varying electronic and steric properties, were prepared and their pKa values were determined in DMSO at 25 °C using the bracketing indicator method. The effect of each systematic structural variation upon the acidity of the triazolium cation has been considered, in particular examining the effects of systematically altering electronic properties, quantified through the use of Hammett σ parameters. The first pKa value for an azolium salt that generates a mesionic carbene is also reported. These new data allow for the selection of appropriate bases for the deprotonation of such triazolium salts and the potential to correlate the pKa values determined herein with the nucleophilicity of the corresponding carbenes.